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Funded Research

Below is a listing of Chemical Diversity projects first funded for the Molecular Libraries (ML) Pilot phase. Under this listing are the Chemical Diversity projects funded at the beginning of the ML Production phase.

Information on Funded Research from all the ML initiatives can be found in the Funded Research section of the website.

First Funded during ML pilot phase

PI Name Institution Name Title
Baures, Paul William University of Tulsa Molecular Libraries from Imidazole-4,5-Dicarboxylic Acid
Burgess, Kevin Texas A&M University System Evolving Libraries of Bivalent Compounds
Georg, Gunda I. University of Minnesota Libraries for HTS: Privileged Structures in Sparsely Populated Chemical Space
Gilbertson, Scott R. University of Texas Medical Br Galveston Synthesis of Pilot Libraries Based on Medicinal Relevant Scaffolds
Gray, Nathanael S. Dana-Farber Cancer Institute Inhibitors of Kinase Activation
Hanson, Paul R. University of Kansas Lawrence Probing Diversity Space with Novel Pilot Scale Libraries
Houghten, Richard A Torrey Pines Institute for Molecular Studies Stereochemically /Structurally Diverse Pilot Scale Library
Houghten, Richard A Torrey Pines Institute for Molecular Studies Highly Diverse and Structurally Varied Heterocyclic Libraries for the MLSMR
Krchnak, Viktor University of Notre Dame Combinational synthesis of bisheterocyclic libraries
Kurth, Mark J. University of California Davis UCD Combinatorial Center - Novel and Diverse Pilot-Scale Library Production
Kwon, Ohyun University of California Los Angeles Pilot-Scale Library Production Based on Phosphine Catalysis of Allenes
Larock, Richard C Iowa State University Heterocyclic /Carbocyclic Libraries for High Throughput
Lee, Kuo-Hsiung University of North Carolina Chapel Hill Chemical Diversity Libraries from Medicinal Plants
Meinwald, Jerrold Cornell University Arthropod-Based Libraries for High Throughput Screening
Parker, Matthew A. Chemdiv, Inc. New Regions of Diversity Space in Ergot-Based Libraries
Porco, John A. Boston University Charles River Campus Generation of Stereochemically and Structurally Complex Chemical Libraries
Schreiber, Stuart L. Massachusetts Institute of Technology Versatile Diversity-oriented Small Molecule Libraries for Chemogenetics
Smith, Amos B. University of Pennsylvania Pilot-Scale Libraries for High-Throughput Screening
Tan, Derek S. University of New Mexico Albuquerque Diversity-Oriented Synthesis of Natural Product-based Libraries for the MLSCN
West, Lyndon M. University of Georgia (UGA) Drug-Like Marine Natural Products Library
Wright, Jeffrey L. University of North Carolina Wilmington Diverse Chemical Libraries from Photosynthetic Marine Microalgae
Zhang, Wei Fluorous Technologies, Inc. Diversity-Oriented Synthesis of Novel Heterocyclic & Natural Product-Like Library

New Methodologies for Natural Products Chemistry Funded Research: RFA-RM-05-013

PI Name Institution Name Title
Burkart, Michael University of California San Diego Proteomic Methodologies for Polyketide Biosynthesis
Doyle, Donald F Georgia Institute of Technology Natural Product Biosynthesis by Chemical Complementation
Handelsman, Jo E University of Wisconsin Madison Intracellular Screens for Discovery of Natural Products in Metagenomic Libraries
Miller, Marvin J University of Notre Dame Novel Derivatization/Functionalization of Natural Products
Orjala, Jimmy University of Illinois At Chicago Microscale LC-MS and NMR Methodology for Rapid Natural Products Chemistry
Wang, Clay C University of Southern California Platforms for Nonribosomal Peptide Manipulation

First Funded during ML production phase