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(336) Indirect Publications in 2008


Abbas, A., & Roth, B. L. (2008). Protein engineering: Electrifying cell receptors. Nature Nanotechnology, 3(10), 587- 588.

Agça, E., Batailler, M., Tillet, Y., Chemineau, P., & Duittoz, A. H. (2008). Modulation of estrogen receptors during development inhibits neurogenesis of precursors to GnRH-1 neurones: In vitro studies with explants of ovine olfactory placode. Brain Research, 1223(C), 34-41.

Albanito, L., Lappano, R., Madeo, A., Chimento, A., Prossnitz, E. R., Cappello, A. R., et al. (2008). G-protein-coupled receptor 30 and estrogen receptor-α are involved in the proliferative effects induced by atrazine in ovarian cancer cells. Environmental Health Perspectives, 116(12), 1648-1655.

Albanito, L., Sisci, D., Aquila, S., Brunelli, E., Vivacqua, A., Madeo, A., et al. (2008). Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells. Endocrinology, 149(8), 3799-3808.

Alewijnse, A. E., & Peters, S. L. M. (2008). Sphingolipid signalling in the cardiovascular system: Good, bad or both? European Journal of Pharmacology, 585(2-3), 292-302.

Allende, M. L., Zhou, D., Kalkofen, D. N., Benhamed, S., Tuymetova, G., Borowski, C., et al. (2008). S1P1 receptor expression regulates emergence of NKT cells in peripheral tissues. FASEB Journal, 22(1), 307-315.

Alyea, R. A., Laurence, S. E., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A., & Watson, C. S. (2008). The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells. Journal of Neurochemistry, 106(4), 1525-1533.

Andersen, L. M., Wind, T., Hansen, H. D., & Andreasen, P. A. (2008). A cyclic peptidylic inhibitor of murine urokinase-type plasminogen activator: Changing species specificity by substitution of a single residue. Biochemical Journal, 412(3), 447-457.

Aragon, A. D., Imani, R. A., Blackburn, V. R., & Cunningham, C. (2008). Microarray based analysis of temperature and oxidative stress induced messenger RNA in schistosoma mansoni. Molecular and Biochemical Parasitology, 162(2), 134-141.

Arany, Z., Wagner, B. K., Ma, Y., Chinsomboon, J., Laznik, D., & Spiegelman, B. M. (2008). Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation. Proceedings of the National Academy of Sciences of the United States of America, 105(12), 4721-4726.

Arias-Loza, P. A., Jazbutyte, V., & Pelzer, T. (2008). Genetic and pharmacologic strategies to determine the function of estrogen receptor α and estrogen receptor β in cardiovascular system. Gender Medicine, 5(SUPPL. 1), S34-S45.

Arnt, J., Bang-Andersen, B., Dias, R., & Bøgesø, K. P. (2008). Strategies for pharmacotherapy of schizophrenia. Drugs of the Future, 33(9), 777-791.

Atkinson, J. M., Siller, C. S., & Gill, J. H. (2008). Tumour endoproteases: The cutting edge of cancer drug delivery? British Journal of Pharmacology, 153(7), 1344-1352.

Babaoglu, K., Simconov, A., Irwin, J. J., Nelson, M. E., Feng, B., Thomas, C. J., et al. (2008). Comprehensive mechanistic analysis of hits from high-throughput and docking screens against β-lactamase. Journal of Medicinal Chemistry, 51(8), 2502-2511.

Bahadoran, P., & Ortonne, J. -. (2008). Viewpoint 5. Experimental Dermatology, 17(2), 158-160.

Bajorath, J. (2008). Computational approaches in chemogenomics and chemical biology: Current and future impact on drug discovery. Expert Opinion on Drug Discovery, 3(12), 1371-1376.

Baron, M. -., Gauchat, D., Motte-Mohs, R. L., Kettaf, N., Abdallah, A., Michiels, T., et al. (2008). TLR ligand-induced type I IFNs affect thymopoiesis. Journal of Immunology, 180(11), 7134-7146.

Bayley, H., Cronin, B., Heron, A., Holden, M. A., Hwang, W. L., Syeda, R., et al. (2008). Droplet interface bilayers. Molecular BioSystems, 4(12), 1191-1208.

Beck-Peccoz, P. (2008). Antithyroid drugs are 65 years old: Time for retirement? Endocrinology, 149(12), 5943-5944.

Berlinck, R. G. S., Burtoloso, A. C. B., & Kossuga, M. H. (2008). The chemistry and biology of organic guanidine derivatives. Natural Product Reports, 25(5), 919-954.

Bevan, M. J., & Fink, P. J. (2008). Immunology: Surprising side effects. Nature, 454(7206), 837-838.

Bharate, S. B., Rodge, A., Joshi, R. K., Kaur, J., Srinivasan, S., Senthil Kumar, S., et al. (2008). Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists. Bioorganic and Medicinal Chemistry Letters, 18(24), 6357-6361.

Bieberich, E. (2008). Smart drugs for smarter stem cells: Making SENSe (sphingolipid-enhanced neural stem cells) of ceramide. NeuroSignals, 16(2-3), 124-139.

Bjelić, S., & Jelesarov, I. (2008). A survey of the year 2007 literature on applications of isothermal titration calorimetry. Journal of Molecular Recognition, 21(5), 289-311.

Bodar, E., Netea, M. G., De Jong, D. J., Kullberg, B. -., Joosten, L. A. B., & Van Der Meer, J. W. M. (2008). NOD2 engagement induces proinflammatory cytokine production, but not apoptosis, in leukocytes isolated from patients with crohn’s disease. European Cytokine Network, 19(4), 185-189.

Borenstein, J. T. (2008). Acting together, bacterial clusters initiate coagulation. Nature Chemical Biology, 4(12), 718-719.

Borensztajn, K., Peppelenbosch, M. P., & Spek, C. A. (2008). Factor xa: At the crossroads between coagulation and signaling in physiology and disease. Trends in Molecular Medicine, 14(10), 429-440.

Bouskine, A., Nebout, M., Mograbi, B., Brücker-Davis, F., Roger, C., & Fenichel, P. (2008). Estrogens promote human testicular germ cell cancer through a membrane-mediated activation of extracellular regulated kinase and protein kinase A. Endocrinology, 149(2), 565-573.

Brady, A. E., Jones, C. K., Bridges, T. M., Kennedy, J. P., Thompson, A. D., Heiman, J. U., et al. (2008). Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats. Journal of Pharmacology and Experimental Therapeutics, 327(3), 941-953.

Breda, A., Basso, L. A., Santos, D. S., & de Azevedo Jr., W. F. (2008). Virtual screening of drugs: Score functions, docking, and drug design. Current Computer-Aided Drug Design, 4(4), 265-272.

Breier, J. M., Radio, N. M., Mundy, W. R., & Shafer, T. J. (2008). Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells. Toxicological Sciences, 105(1), 119-133.

Bridges, T. M., & Lindsley, C. W. (2008). G-protein-coupled receptors: From classical modes of modulation to allosteric mechanisms. ACS Chemical Biology, 3(9), 530-541.

Brochu, J. -., Prakesch, M., Enright, G. D., Leek, D. M., & Arya, P. (2008). Reagent-based, modular, tandem michael approach for obtaining different indoline alkaloid-inspired polycyclic architectures. Journal of Combinatorial Chemistry, 10(3), 405-420.

Cahalan, M. D., & Parker, I. (2008). Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs

Carroll, S. M., Bridgham, J. T., & Thornton, J. W. (2008). Evolution of hormone signaling in elasmobranchs by exploitation of promiscuous receptors. Molecular Biology and Evolution, 25(12), 2643-2652.

Castoria, G., Migliaccio, A., D’Amato, L., Di Stasio, R., Ciociola, A., Lombardi, M., et al. (2008). Integrating signals between cAMP and MAPK pathways in breast cancer. Frontiers in Bioscience, 13(4), 1318-1327.

Chan, A. C. (2008). A golden era of opportunity in immunotherapy discovery and development. Immunological Reviews, 223(1), 5-6.

Chappell, K. J., Stoermer, M. J., Fairlie, D. P., & Young, P. R. (2008). West nile virus NS2B/NS3 protease as an antiviral target. Current Medicinal Chemistry, 15(27), 2771-2784.

Chee, M. J. S., Mörl, K., Lindner, D., Merten, N., Zamponi, G. W., Light, P. E., et al. (2008). The third intracellular loop stabilizes the inactive state of the neuropeptide Y1 receptor. Journal of Biological Chemistry, 283(48), 33337-33346.

Chen, G. G., Zeng, Q., & Tse, G. M. K. (2008). Estrogen and its receptors in cancer. Medicinal Research Reviews, 28(6), 954-974.

Cheng, A. C. (2008). Chapter 2 predicting selectivity and druggability in drug discovery

Cheng, L. S., Amaro, R. E., Xu, D., Li, W. W., Arzberger, P. W., & McCammon, J. A. (2008). Ensemble-based virtual screening reveals potential novel antiviral compounds for avian influenza neuraminidase. Journal of Medicinal Chemistry, 51(13), 3878-3894.

Chico, T. J. A., Ingham, P. W., & Crossman, D. C. (2008). Modeling cardiovascular disease in the zebrafish. Trends in Cardiovascular Medicine, 18(4), 150-155.

Christiansen, E., Urban, C., Merten, N., Liebscher, K., Karlsen, K. K., Hamacher, A., et al. (2008). Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA1/GPR40), a potential target for the treatment of type II diabetes. Journal of Medicinal Chemistry, 51(22), 7061-7064.

Cinamon, G., Zachariah, M. A., Lam, O. M., Foss Jr., F. W., & Cyster, J. G. (2008). Follicular shuttling of marginal zone B cells facilitates antigen transport. Nature Immunology, 9(1), 54-62.

Cioli, D., Valle, C., Angelucci, F., & Miele, A. E. (2008). Will new antischistosomal drugs finally emerge? Trends in Parasitology, 24(9), 379-382.

Cloutier, L. M., & Sirois, S. (2008). Bayesian versus frequentist statistical modeling: A debate for hit selection from HTS campaigns. Drug Discovery Today, 13(11-12), 536-542.

Collins, F. S., Gray, G. M., & Bucher, J. R. (2008). Transforming environmental health protection. Science, 319(5865), 906-907.

Conn, P. J., & Roth, B. L. (2008). Opportunities and challenges of psychiatric drug discovery: Roles for scientists in academic, industry, and government settings. Neuropsychopharmacology, 33(9), 2048-2060.

Corrie, S. R., Lawrie, G. A., Battersby, B. J., Ford, K., Rühmann, A., Koehler, K., et al. (2008). Quantitative data analysis methods for bead-based DNA hybridization assays using generic flow cytometry platforms. Cytometry Part A, 73(5), 467-476.

Counceller, C. M., Eichman, C. C., Wray, B. C., & Stambuli, J. P. (2008). A practical, metal-free synthesis of 1H-lndazoles. Organic Letters, 10(5), 1021-1023.

Crawford, A. D., Esguerra, C. V., & De Witte, P. A. M. (2008). Fishing for drugs from nature: Zebrafish as a technology platform for natural product discovery. Planta Medica, 74(6), 624-632.

Cusatis, G., & Sparreboom, A. (2008). Pharmacogenomic importance of ABCG2. Pharmacogenomics, 9(8), 1005-1009.

Daigeler, A., Brenzel, C., Bulut, D., Geisler, A., Hilgert, C., Lehnhardt, M., et al. (2008). TRAIL and taurolidine induce apoptosis and decrease proliferation in human fibrosarcoma. Journal of Experimental and Clinical Cancer Research, 27(1)

Damm, K. L., Ung, P. M. U., Quintero, J. J., Gestwicki, J. E., & Carlson, H. A. (2008). A poke in the eye: Inhibiting HIV-1 protease through its flap-recognition pocket. Biopolymers, 89(8), 643-652.

de Kloet, E. R., Karst, H., & Joëls, M. (2008). Corticosteroid hormones in the central stress response: Quick-and-slow. Frontiers in Neuroendocrinology, 29(2), 268-272.

de Oliveira Penido, M. L., Zech Coelho, P. M., de Mello, R. T., Piló-Veloso, D., de Oliveira, M. C., Kusel, J. R., et al. (2008). Antischistosomal activity of aminoalkanethiols, aminoalkanethiosulfuric acids and the corresponding disulfides. Acta Tropica, 108(2-3), 249-255.

Degterev, A., & Yuan, J. (2008). Expansion and evolution of cell death programmes. Nature Reviews Molecular Cell Biology, 9(5), 378-390.

Deiters, E., Song, B., Chauvin, A. -., Vandevyver, C. D. B., & Bünzli, J. -. G. (2008). Effect of the length of polyoxyethylene substituents on luminescent bimetallic lanthanide bioprobes. New Journal of Chemistry, 32(7), 1140-1152.

Derler, I., Fritsch, R., Schindl, R., & Romanin, C. (2008). CRAC inhibitors: Identification and potential. Expert Opinion on Drug Discovery, 3(7), 787-800.

Dev, K. K., Mullershausen, F., Mattes, H., Kuhn, R. R., Bilbe, G., Hoyer, D., et al. (2008). Brain sphingosine-1-phosphate receptors: Implication for FTY720 in the treatment of multiple sclerosis. Pharmacology and Therapeutics, 117(1), 77-93.

Doenhoff, M. J., Cioli, D., & Utzinger, J. (2008). Praziquantel: Mechanisms of action, resistance and new derivatives for schistosomiasis. Current Opinion in Infectious Diseases, 21(6), 659-667.

Dolle, R. E., Le Bourdonnec, B., Goodman, A. J., Morales, G. A., Thomas, C. J., & Zhang, W. (2008). Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2007. Journal of Combinatorial Chemistry, 10(6), 753-802.

Dostert, C., Meylan, E., & Tschopp, J. (2008). Intracellular pattern-recognition receptors. Advanced Drug Delivery Reviews, 60(7), 830-840.

Dragunow, M. (2008). High-content analysis in neuroscience. Nature Reviews Neuroscience, 9(10), 779-788.

Dubois, J., Bourg, S., Vrain, C., & Morin-Allory, L. (2008). Collections of compounds – how to deal with them? Current Computer-Aided Drug Design, 4(3), 156-168.

Dudek, P., & Picard, D. (2008). Genomics of signaling crosstalk of estrogen receptor α in breast cancer cells. PLoS ONE, 3(3)

Dyatlovitskaya, E. V. (2008). Sphingolipid receptors. Biochemistry (Moscow), 73(2), 119-122.

Eckenhoff, R. G., Zheng, W., & Kelz, M. B. (2008). From anesthetic mechanisms research to drug discovery. Clinical Pharmacology and Therapeutics, 84(1), 144-148.

Edwards, P. J. (2008). Combinatorial library methodology applied to cancer and protease targets. thiazolidinone derivatives targeting drug-resistant lung cancer cells. Drug Discovery Today, 13(23-24), 1107-1108.

Eglen, R. M. (2008). Screening the human kinome – expectations met or promises pending? Drug Discovery World, 9(3), 21-32.

Eimon, P. (2008). Disease modelling and toxicity screening in transgenic zebrafish embryos. Bio Tech International, 20(2), 12-15.

Engel, S., Skoumbourdis, A. P., Childress, J., Neumann, S., Deschamps, J. R., Thomas, C. J., et al. (2008). A virtual screen for diverse ligands: Discovery of selective G protein-coupled receptor antagonists. Journal of the American Chemical Society, 130(15), 5115-5123.

Enna, S. J., Feuerstein, G. Z., Piette, J., & Williams, M. (2008). Fifty years of biochemical pharmacology: The discipline and the journal. Biochemical Pharmacology, 76(1), 1-10.

Enns, G. M., & Huhn, S. L. (2008). Central nervous system therapy for lysosomal storage disorders. Neurosurgical Focus, 24(3-4)

Erdélyi, M., Pfeiffer, B., Hauenstein, K., Fohrer, J., Gertsch, J., Altmann, K. -., et al. (2008). Conformational preferences of natural and C3-modified epothilones in aqueous solution. Journal of Medicinal Chemistry, 51(5), 1469-1473.

Fadeel, B., Ottosson, A., & Pervaiz, S. (2008). Big wheel keeps on turning: Apoptosome regulation and its role in chemoresistance. Cell Death and Differentiation, 15(3), 443-452.

Fattori, D., Squarcia, A., & Bartoli, S. (2008). Fragment-based approach to drug lead discovery: Overview and advances in various techniques. Drugs in R and D, 9(4), 217-227.

Faulon, J. -., Misra, M., Martin, S., Sale, K., & Sapra, R. (2008). Genome scale enzyme – metabolite and drug – target interaction predictions using the signature molecular descriptor. Bioinformatics, 24(2), 225-233.

Federico, L., Pamuklar, Z., Smyth, S. S., & Morris, A. J. (2008). Therapeutic potential of autotaxin/lysophospholipase D inhibitors. Current Drug Targets, 9(8), 698-708.

Fei, H., & Huan, J. (2008). Structure feature selection for chemical compound classification. Paper presented at the

Fernandes-Alnemri, T., & Alnemri, E. S. (2008). Chapter thirteen assembly, purification, and assay of the activity of the ASC pyroptosome

Ferwerda, G., Kramer, M., de Jong, D., Piccini, A., Joosten, L. A., DevesaGiner, I., et al. (2008). Engagement of NOD2 has a dual effect on proIL-1β mRNA transcription and secretion of bioactive IL-1β. European Journal of Immunology, 38(1), 184-191.

Fluxá, V. S., Wahler, D., & Reymond, J. -. (2008). Enzyme assay and activity fingerprinting of hydrolases with the red-chromogenic adrenaline test. Nature Protocols, 3(8), 1270-1277.

Fotouhi, N., Gillespie, P., & Goodnow Jr., R. (2008). Lead generation: Reality check on commonly held views. Expert Opinion on Drug Discovery, 3(7), 733-744.

Gaide, O., & Hoffman, H. M. (2008). Insight into the inflammasome and caspase-activating mechanisms. Expert Review of Clinical Immunology, 4(1), 61-77.

Giannetti, A. M., Koch, B. D., & Browner, M. F. (2008). Surface plasmon resonance based assay for the detection and characterization of promiscuous inhibitors. Journal of Medicinal Chemistry, 51(3), 574-580.

Glinsky, G. V. (2008). SNP-guided microRNA maps (MirMaps) of 16 common human disorders identify a clinically accessible therapy reversing transcriptional aberrations of nuclear import and inflammasome pathways. Cell Cycle, 7(22), 3564-3576.

Gohda, M., Kunisawa, J., Miura, F., Kagiyama, Y., Kurashima, Y., Higuchi, M., et al. (2008). Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from peyer’s patches for intestinal IgA responses. Journal of Immunology, 180(8), 5335-5343.

Goode, D. R., Totten, R. K., Heeres, J. T., & Hergenrother, P. J. (2008). Identification of promiscuous small molecule activators in high-throughput enzyme activation screens. Journal of Medicinal Chemistry, 51(8), 2346-2349.

Gou, L., Lü, Z. -., Park, D., Sang, H. O., Shi, L., Seong, J. P., et al. (2008). The effect of histidine residue modification on tyrosinase activity and conformation: Inhibition kinetics and computational prediction. Journal of Biomolecular Structure and Dynamics, 26(3), 395-401.

Grabowski, K., Baringhaus, K. -., & Schneider, G. (2008). Scaffold diversity of natural products: Inspiration for combinatorial library design. Natural Product Reports, 25(5), 892-904.

Gregori-Puigjané, E., & Mestres, J. (2008). A ligand-based approach to mining the chemogenomic space of drugs. Combinatorial Chemistry and High Throughput Screening, 11(8), 669-676.

Gribbon, P. (2008). High-throughput hit finding and compound-profiling technologies for academic drug discovery. Drug Discovery Today: Technologies, 5(1), e3-e7.

Grimberg, B. T., Erickson, J. J., Sramkoski, R. M., Jacobberger, J. W., & Zimmerman, P. A. (2008). Monitoring plasmodium falciparum growth and development by UV flow cytometry using an optimized hoechst-thiazole orange staining strategy. Cytometry Part A, 73(6), 546-554.

Gross, B. J., Swoboda, J. G., & Walker, S. (2008). A strategy to discover inhibitors of O-linked glycosylation. Journal of the American Chemical Society, 130(2), 440-441.

Gude, D. R., Alvarez, S. E., Paugh, S. W., Mitra, P., Yu, J., Griffiths, R., et al. (2008). Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a “come-and-get-me” signal. FASEB Journal, 22(8), 2629-2638.

Guido, R. V. C., Oliva, G., & Andricopulo, A. D. (2008). Virtual screening and its integration with modern drug design technologies. Current Medicinal Chemistry, 15(1), 37-46.

Hall, C. J., Flores, M. V., Crosier, K. E., & Crosier, P. S. (2008). Live imaging early immune cell ontogeny and function in zebrafish danio rerio. Journal of Fish Biology, 73(8), 1833-1871.

Hämäläinen, M. D., Zhukov, A., Ivarsson, M., Fex, T., Gottfries, J., Karlsson, R., et al. (2008). Label-free primary screening and affinity ranking of fragment libraries using parallel analysis of protein panels. Journal of Biomolecular Screening, 13(3), 202-209.

Harvell, D. M. E., Spoelstra, N. S., Singh, M., McManaman, J. L., Finlayson, C., Phang, T., et al. (2008). Molecular signatures of neoadjuvant endocrine therapy for breast cancer: Characteristics of response or intrinsic resistance. Breast Cancer Research and Treatment, 112(3), 475-488.

Hassan, G. S., Farag, N. A., Hegazy, G. H., & Arafa, R. K. (2008). Design and synthesis of novel benzopyran-2-one derivatives of expected antimicrobial activity through DNA gyrase-B inhibition. Archiv Der Pharmazie, 341(11), 725-733.

He, D., Natarajan, V., Stern, R., Gorshkova, I. A., Solway, J., Spannhake, E. W., et al. (2008). Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E2 release via C/EBPβ in human bronchial epithelial cells. Biochemical Journal, 412(1), 153-162.

Heinonen, K. M., & Perreault, C. (2008). Development and functional properties of thymic and extrathymic T lymphocytes. Critical Reviews in Immunology, 28(5), 441-466.

Heitman, L. H., Van Veldhoven, J. P. D., Zweemer, A. M., Ye, K., Brussee, J., & Ijzerrnan, A. P. (2008). False positives in a reporter gene assay: Identification and synthesis of substituted N-pyridin-2-ylbenzamides as competitive inhibitors of firefly luciferase. Journal of Medicinal Chemistry, 51(15), 4724-4729.

Herold, C. D., Nguyen, B. T., & Rothwarf, D. M. (2008). A novel, scalable liquid array platform. JALA – Journal of the Association for Laboratory Automation, 13(6), 344-350.

Hiestand, P. C., Rausch, M., Meier, D. P., & Foster, C. A. (2008). Ascomycete derivative to MS therapeutic: S1P receptor modulator FTY720

Hinkovska-Galcheva, V., VanWay, S. M., Shanley, T. P., & Kunkel, R. G. (2008). The role of sphingosine-1-phosphate and ceramide-1-phosphate in calcium homeostasis. Current Opinion in Investigational Drugs, 9(11), 1192-1205.

Hla, T., Venkataraman, K., & Michaud, J. (2008). The vascular S1P gradient-cellular sources and biological significance. Biochimica Et Biophysica Acta – Molecular and Cell Biology of Lipids, 1781(9), 477-482.

Högenauer, K., Billich, A., Pally, C., Streiff, M., Wagner, T., Welzenbach, K., et al. (2008). Phosphorylation by sphingosine kinase 2 is essential for in vivo potency of FTY720 analogues. ChemMedChem, 3(7), 1027-1029.

Hogquist, K. A., Weinreich, M. A., & Jameson, S. C. (2008). T-cell migration: Kruppeled T cells move again. Immunology and Cell Biology, 86(4), 297-298.

Horga, A., & Montalban, X. (2008). FTY720 (fingolimod) for relapsing multiple sclerosis. Expert Review of Neurotherapeutics, 8(5), 699-714.

Houck, K. A., & Kavlock, R. J. (2008). Understanding mechanisms of toxicity: Insights from drug discovery research. Toxicology and Applied Pharmacology, 227(2), 163-178.

Hozjan, V., Guo, K., Wu, X., & Oppermann, U. (2008). Ligand supplementation as a method to increase soluble heterologous protein production. Expert Review of Proteomics, 5(1), 137-143.

Hsieh, J. -., Wang, X. S., Teotico, D., Golbraikh, A., & Tropsha, A. (2008). Differentiation of AmpC beta-lactamase binders vs. decoys using classification kNN QSAR modeling and application of the QSAR classifier to virtual screening. Journal of Computer-Aided Molecular Design, 22(9), 593-609.

Hsu, L. -., Ali, S. R., McGillivray, S., Tseng, P. -., Mariathasan, S., Humke, E. W., et al. (2008). A NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to bacillus anthracis infection and muramyl dipeptide. Proceedings of the National Academy of Sciences of the United States of America, 105(22), 7803-7808.

Hu, P., Kinyamu, H. K., Wang, L., Martin, J., Archer, T. K., & Teng, C. (2008). Estrogen induces estrogen-related receptor α gene expression and chromatin structural changes in estrogen receptor (ER)-positive and ER-negative breast cancer cells. Journal of Biological Chemistry, 283(11), 6752-6763.

Huang, J. -., Cheng, H. -., Chiang, C. -., Hung, K. -., & Tsai, T. -. (2008). Lysophosphatidic acid and renal fibrosis. Recent Patents on Endocrine, Metabolic and Immune Drug Discovery, 2(3), 204-210.

Hübel, K., Leßmann, T., & Waldmann, H. (2008). Chemical biology – identification of small molecule modulators of cellular activity by natural product inspired synthesis. Chemical Society Reviews, 37(7), 1361-1374.

Huber, T., Menon, S., & Sakmar, T. P. (2008). Structural basis for ligand binding and specificity in adrenergic receptors: Implications for GPCR-targeted drug discovery. Biochemistry, 47(42), 11013-11023.

Huebner, A., Olguin, L. F., Bratton, D., Whyte, G., Huck, W. T. S., De Mello, A. J., et al. (2008). Development of quantitative cell-based enzyme assays in microdroplets. Analytical Chemistry, 80(10), 3890-3896.

Hur, J., & Wild, D. J. (2008). PubChemSR: A search and retrieval tool for PubChem. Chemistry Central Journal, 2(1)

Ibáñez-Peral, R., Bergquist, P. L., Walter, M. R., Gibbs, M., Goldys, E. M., & Ferrari, B. (2008). Potential use of quantum dots in flow cytometry. International Journal of Molecular Sciences, 9(12), 2622-2638.

Itokawa, H., Morris-Natschke, S. L., Akiyama, T., & Lee, K. -. (2008). Plant-derived natural product research aimed at new drug discovery. Journal of Natural Medicines, 62(3), 263-280.

Ivinson, A. J., Lane, R., May, P. C., Hosford, D. A., Carrillo, M. C., & Siemers, E. R. (2008). Partnership between academia and industry for drug discovery in alzheimer’s disease. Alzheimer’s and Dementia, 4(2), 80-88.

Javitt, N. B. (2008). Oxysterols: Novel biologic roles for the 21st century. Steroids, 73(2), 149-157.

Jensen, N. H., & Roth, B. L. (2008). Massively parallel screening of the receptorome. Combinatorial Chemistry and High Throughput Screening, 11(6), 420-426.

Jiang, X., Patterson, N. M., Ling, Y., Xie, J., Helferich, W. G., & Shapiro, D. J. (2008). Low concentrations of the soy phytoestrogen genistein induce proteinase inhibitor 9 and block killing of breast cancer cells by immune cells. Endocrinology, 149(11), 5366-5373.

Jo, S. -., Bajwa, A., Awad, A. S., Lynch, K. R., & Okusa, M. D. (2008). Sphingosine-1-phosphate receptors: Biology and therapeutic potential in kidney disease. Kidney International, 73(11), 1220-1230.

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