Skip Navigation
  

Related Links

(350) Indirect Publications in 2009

Abdul-Ghani, R., Loutfy, N., Sahn, A. E., & Hassan, A. (2009). Current chemotherapy arsenal for schistosomiasis mansoni: Alternatives and challenges. Parasitology Research, 104(5), 955-965.

Abdul-Ghani, R. A., Loutfy, N., & Hassan, A. (2009). Experimentally promising antischistosomal drugs: A review of some drug candidates not reaching the clinical use. Parasitology Research, 105(4), 899-906.

Abulafia, D. P., De Rivero Vaccari, J. P., Lozano, J. D., Lotocki, G., Keane, R. W., & Dietrich, W. D. (2009). Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice. Journal of Cerebral Blood Flow and Metabolism, 29(3), 534-544.

Allgeier, S. H., Vezina, C. M., Lin, T. -., Moore, R. W., Silverstone, A. E., Mukai, M., et al. (2009). Estrogen signaling is not required for prostatic bud patterning or for its disruption by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology and Applied Pharmacology, 239(1), 80-86.

Ananthan, S., Zhang, W., & Hobrath, J. V. (2009). Recent advances in structure-based virtual screening of G-protein coupled receptors. AAPS Journal, 11(1), 178-185.

Andersen, M. E., & Krewski, D. (2009). Toxicity testing in the 21st century: Bringing the vision to life. Toxicological Sciences, 107(2), 324-330.

Angelopoulos, N., Hadjiprocopis, A., & Walkinshaw, M. D. (2009). Bayesian model averaging for ligand discovery. Journal of Chemical Information and Modeling, 49(6), 1547-1557.

Antony, J., Kellershohn, K., Mohr-Andrä, M., Kebig, A., Prilla, S., Muth, M., et al. (2009). Dualsteric GPCR targeting: A novel route to binding and signaling pathway selectivity. FASEB Journal, 23(2), 442-450.

Arkin, M. R., & Whitty, A. (2009). The road less traveled: Modulating signal transduction enzymes by inhibiting their protein-protein interactions. Current Opinion in Chemical Biology, 13(3), 284-290.

Auld, D. S., Zhang, Y. -., Southall, N. T., Rai, G., Landsman, M., MacLure, J., et al. (2009). A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. Journal of Medicinal Chemistry, 52(5), 1450-1458.

Bachovchin, D. A., Brown, S. J., Rosen, H., & Cravatt, B. F. (2009). Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes. Nature Biotechnology, 27(4), 387-394.

Barton, M., & Meyer, M. R. (2009). Postmenopausal hypertension: Mechanisms and therapy. Hypertension, 54(1), 11-18.

Baškovč, J., Bevk, D., Stanovnik, B., & Svete, J. (2009). Bis-enaminone based parallel solution-phase synthesis of 1,4-dihydropyridine derivatives. Journal of Combinatorial Chemistry, 11(3), 500-507.

Baxendale, I. R., Ley, S. V., Mansfield, A. C., & Smith, C. D. (2009). Multistep synthesis using modular flow reactors: Bestmann-ohira reagent for the formation of alkynes and triazoles. Angewandte Chemie – International Edition, 48(22), 4017-4021.

Bayne, C. J. (2009). Successful parasitism of vector snail biomphalaria glabrata by the human blood fluke (trematode) schistosoma mansoni: A 2009 assessment. Molecular and Biochemical Parasitology, 165(1), 8-18.

Bergsbaken, T., Fink, S. L., & Cookson, B. T. (2009). Pyroptosis: Host cell death and inflammation. Nature Reviews Microbiology, 7(2), 99-109.

Berrodin, T. J., Chang, K. C. N., Komm, B. S., Freedman, L. P., & Nagpal, S. (2009). Differential biochemical and cellular actions of premarin estrogens: Distinct pharmacology of bazedoxifene-conjugated estrogens combination. Molecular Endocrinology, 23(1), 74-85.

Bharate, S. B., Nemmani, K. V. S., & Vishwakarma, R. A. (2009). Progress in the discovery and development of small-molecule modulators of G-protein-coupled receptor 40 (GPR40/FFA1/FFAR1): An emerging target for type 2 diabetes. Expert Opinion on Therapeutic Patents, 19(2), 237-264.

Bickel, P. E., Tansey, J. T., & Welte, M. A. (2009). PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores. Biochimica Et Biophysica Acta – Molecular and Cell Biology of Lipids, 1791(6), 419-440.

Biersack, B., & Schobert, R. (2009). Metallodrug conjugates with steroids and selective estrogen receptor modulators (SERM). Current Medicinal Chemistry, 16(18), 2324-2337.

Biffinger, J., Ribbens, M., Ringeisen, B., Pietron, J., Finkel, S., & Nealson, K. (2009). Characterization of electrochemically active bacteria utilizing a high-throughput voltage-based screening assay. Biotechnology and Bioengineering, 102(2), 436-444.

Blackburn, W. H., Dickerson, E. B., Smith, M. H., McDonald, J. F., & Lyon, L. A. (2009). Peptide-functionalized nanogels for targeted siRNA delivery. Bioconjugate Chemistry, 20(5), 960-968.

Blaskovich, M. A. T. (2009). Drug discovery and protein tyrosine phosphatases. Current Medicinal Chemistry, 16(17), 2095-2176.

Blom, W. M., van Nielen, W. G. L., de Groene, E. M., & Albers, R. (2009). A cell-based screening assay for natural killer cell activity. International Immunopharmacology, 9(6), 746-752.

Blum, L. C., & Reymond, J. -. (2009). 970 million druglike small molecules for virtual screening in the chemical universe database GDB-13. Journal of the American Chemical Society, 131(25), 8732-8733.

Bogdan, A. R., & Sach, N. W. (2009). The use of copper flow reactor technology for the continuous synthesis of 1,4-disubstituted 1,2,3-triazoles. Advanced Synthesis and Catalysis, 351(6), 849-854.

Boisselier, E., & Astruc, D. (2009). Gold nanoparticles in nanomedicine: Preparations, imaging, diagnostics, therapies and toxicity. Chemical Society Reviews, 38(6), 1759-1782.

Bourque, M., Dluzen, D. E., & Di Paolo, T. (2009). Neuroprotective actions of sex steroids in parkinson’s disease. Frontiers in Neuroendocrinology, 30(2), 142-157.

Bouskine, A., Nebout, M., Brücker-Davis, F., Banahmed, M., & Fenichel, P. (2009). Low doses of bisphenol A promote human seminoma cell proliferation by activating PKA and PKG via a membrane G-protein-coupled estrogen receptor. Environmental Health Perspectives, 117(7), 1053-1058.

Brady, L. S., Winsky, L., Goodman, W., Oliveri, M. E., & Stover, E. (2009). NIMH initiatives to facilitate collaborations among industry, academia, and government for the discovery and clinical testing of novel models and drugs for psychiatric disorders. Neuropsychopharmacology, 34(1), 229-243.

Brannan, J. M., Dong, W., Prudkin, L., Behrens, C., Lotan, R., Bekele, B. N., et al. (2009). Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non -small cell lung cancer. Clinical Cancer Research, 15(13), 4423-4430.

Brinton, R. D. (2009). Estrogen-induced plasticity from cells to circuits: Predictions for cognitive function. Trends in Pharmacological Sciences, 30(4), 212-222.

Brufani, M., Ceccacci, F., Filocamo, L., Garofalo, B., Joudioux, R., Bella, A. L., et al. (2009). Novel locally active estrogens accelerate cutaneous wound healing. A preliminary study. Molecular Pharmaceutics, 6(2), 543-556.

Bryant, C., & Fitzgerald, K. A. (2009). Molecular mechanisms involved in inflammasome activation. Trends in Cell Biology, 19(9), 455-464.

Burr, I., Winchester, T., Keighley, W., & Sewing, A. (2009). Compound management beyond efficiency. Journal of Biomolecular Screening, 14(5), 485-491.

Caffrey, C. R., Rohwer, A., Oellien, F., Marhöfer, R. J., Braschi, S., Oliveira, G., et al. (2009). A comparative chemogenomics strategy to predict potential drug targets in the metazoan pathogen, schistosoma mansoni. PLoS ONE, 4(2)

Camerer, E., Regard, J. B., Cornelissen, I., Srinivasan, Y., Duong, D. N., Palmer, D., et al. (2009). Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice. Journal of Clinical Investigation, 119(7), 1871-1879.

Campbell, W. C., Conder, G. A., & Marchiondo, A. A. (2009). Future of the animal health industry at a time of food crisis. Veterinary Parasitology, 163(3), 188-195.

Card, A., Caldwell, C., Min, H., Lokchander, B., Xi, H., Sciabola, S., et al. (2009). High-throughput biochemical kinase selectivity assays: Panel development and screening applications. Journal of Biomolecular Screening, 14(1), 31-42.

Castellino, F. J., & Ploplis, V. A. (2009). The protein C pathway and pathologic processes. Journal of Thrombosis and Haemostasis, 7(SUPPL. 1), 140-145.

Chae, J. J., Aksentijevich, I., & Kastner, D. L. (2009). Advances in the understanding of familial mediterranean fever and possibilities for targeted therapy. British Journal of Haematology, 146(5), 467-478.

Chang, E., Congdon, E. E., Honson, N. S., Duff, K. E., & Kuret, J. (2009). Structure-activity relationship of cyanine tau aggregation inhibitors. Journal of Medicinal Chemistry, 52(11), 3539-3547.

Chen, C. -., & Reamer, R. A. (2009). A facile synthesis of N,3-disubstituted indoles and 3-hydroxyl indolines via an intramolecular SNAr of fluorinated amino alcohols. Tetrahedron Letters, 50(14), 1529-1532.

Chen, G., Shaw, M. H., Kim, Y. -., & Nuñez, G. (2009). NOD-like receptors: Role in innate immunity and inflammatory disease

Chu, Z., Andrade, J., Shupnik, M. A., & Moenter, S. M. (2009). Differential regulation of gonadotropin-releasing hormone neuron activity and membrane properties by acutely applied estradiol: Dependence on dose and estrogen receptor subtype. Journal of Neuroscience, 29(17), 5616-5627.

Clapham, K. M., Batsanov, A. S., Bryce, M. R., & Tarbit, B. (2009). Trifluoromethyl-substituted pyridyl- and pyrazolylboronic acids and esters: Synthesis and suzuki-miyaura cross-coupling reactions. Organic and Biomolecular Chemistry, 7(10), 2155-2161.

Clarke, D. L., Dakshinamurti, S., Larsson, A. -., Ward, J. E., & Yamasaki, A. (2009). Lipid metabolites as regulators of airway smooth muscle function. Pulmonary Pharmacology and Therapeutics, 22(5), 426-435.

Codocedo, J. F., Rodríguez, F. E., & Huidobro-Toro, J. P. (2009). Neurosteroids differentially modulate P2X4 ATP-gated channels through non-genomic interactions. Journal of Neurochemistry, 110(2), 734-744.

Coma, I., Clark, L., Diez, E., Harper, G., Herranz, J., Hofmann, G., et al. (2009). Process validation and screen reproducibility in high-throughput screening. Journal of Biomolecular Screening, 14(1), 66-76.

Conn, P. J., Jones, C. K., & Lindsley, C. W. (2009). Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders. Trends in Pharmacological Sciences, 30(3), 148-155.

Cornil, C. A. (2009). Rapid regulation of brain oestrogen synthesis: The behavioural roles of oestrogens and their fates. Journal of Neuroendocrinology, 21(3), 217-226.

Corona, G., Elia, C., Casetta, B., Diana, C., Rosalen, S., Bari, M., et al. (2009). A liquid chromatography-tandemmass spectrometry method for the simultaneous determination of exemestane and its metabolite 17-dihydroexemestane in human plasma. Journal of Mass Spectrometry, 44(6), 920-928.

Creton, R. (2009). Automated analysis of behavior in zebrafish larvae. Behavioural Brain Research, 203(1), 127-136.

D’Anglemont De Tassigny, X., Campagne, C., Steculorum, S., & Prevot, V. (2009). Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor activation in primary neuronal cultures. Journal of Neurochemistry, 109(1), 214-224.

Damodaran, K., Nielsen, S. D., Geib, S. J., Zhang, W., Lu, Y., & Curran, D. P. (2009). Aryl-Csp3 bond rotation barriers of 2-aryl perhydropyrrolo[3,4- c]pyrrole-1,3-diones. Journal of Organic Chemistry, 74(15), 5481-5485.

Danot, O., Marquenet, E., Vidal-Ingigliardi, D., & Richet, E. (2009). Wheel of life, wheel of death: A mechanistic insight into signaling by STAND proteins. Structure, 17(2), 172-182.

de Azevedo Jr., W. F., Dias, R., Timmers, L. F. S. M., Pauli, I., Caceres, R. A., & Soares, M. B. P. (2009). Bioinformatics tools for screening of antiparasitic drugs. Current Drug Targets, 10(3), 232-239.

de Azevedo Jr., W. F., Caceres, R. A., Pauli, I., Timmers, L. F. S. M., Barcellos, G. B., Rocha, K. B., et al. (2009). Protein-drug interaction studies for development of drugs against plasmodium falciparum. Current Drug Targets, 10(3), 271-278.

de Kloe, G. E., Bailey, D., Leurs, R., & de Esch, I. J. P. (2009). Transforming fragments into candidates: Small becomes big in medicinal chemistry. Drug Discovery Today, 14(13-14), 630-646.

De Paoli, P. (2009). Institutional shared resources and translational cancer research. Journal of Translational Medicine, 7

De Wael, F., Jeanjot, P., Moens, C., Verbeuren, T., Cordi, A., Bouskela, E., et al. (2009). In vitro and in vivo studies of 6,8-(diaryl)imidazo[1,2-a]pyrazin-3(7H)-ones as new antioxidants. Bioorganic and Medicinal Chemistry, 17(13), 4336-4344.

Debotton, N., Giladi, O., Parnes, M., & Benita, S. (2009). Novel high-content paclitaxel palmitate nanospheres for improved cancer treatment. Journal of Drug Delivery Science and Technology, 19(4), 275-282.

Delomenède, M., Buchet, R., & Mebarek, S. (2009). Lansoprazole is an uncompetitive inhibitor of tissue-nonspecific alkaline phosphatase. Acta Biochimica Polonica, 56(2), 301-306.

Demian, D. J., Clugston, S. L., Foster, M. M., Rameh, L., Sarkes, D., Townson, S. A., et al. (2009). High-throughput, cell-free, liposome-based approach for assessing in vitro activity of lipid kinases. Journal of Biomolecular Screening, 14(7), 838-844.

Deshmukh, S. K., Mishra, P. D., Kulkarni-Almeida, A., Verekar, S., Sahoo, M. R., Periyasamy, G., et al. (2009). Anti-inflammatory and anticancer activity of ergoflavin isolated from an endophytic fungus. Chemistry and Biodiversity, 6(5), 784-789.

Diamond, M. S. (2009). Progress on the development of therapeutics against west nile virus. Antiviral Research, 83(3), 214-227.

Ding, X. -., Zhang, H. -., Qi, L., Zhao, B. -., Lian, S., Lv, H. -., et al. (2009). Synthesis of novel pyrazole carboxamide derivatives and discovery of modulators for apoptosis or autophagy in A549 lung cancer cells. Bioorganic and Medicinal Chemistry Letters, 19(18), 5325-5328.

Dissous, C., Ahier, A., & Long, T. (2009). A new promising drug against schistosomiasis. [Un nouvel espoir dans le traitement de la schistosomiase] Medecine/Sciences, 25(1), 24-26.

Doghman, M., & Lalli, E. (2009). A matter of dosage: SF-1 in adrenocortical development and cancer. Annales d’Endocrinologie, 70(3), 148-152.

dos Santos Filho, J. M., Leite, A. C. L., Oliveira, B. G. d., Moreira, D. R. M., Lima, M. S., Soares, M. B. P., et al. (2009). Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-trypanosoma cruzi agents. Bioorganic and Medicinal Chemistry, 17(18), 6682-6691.

Drennan, M. B., Elewaut, D., & Hogquist, K. A. (2009). Thymic emigration: Sphingosine-1-phosphate receptor-1-dependent models and beyond. European Journal of Immunology, 39(4), 925-930.

Duerfeldt, A. S., Brandt, G. E. L., & Blagg, B. S. J. (2009). Design, synthesis, and biological evaluation of conformationally constrained cis-amide HSP90 inhibitors. Organic Letters, 11(11), 2353-2356.

Dunworth, W. P., & Caron, K. M. (2009). G protein-coupled receptors as potential drug targets for lymphangiogenesis and lymphatic vascular diseases. Arteriosclerosis, Thrombosis, and Vascular Biology, 29(5), 650-656.

Eglen, R. M., & Reisine, T. (2009). The current status of drug discovery against the human kinome. Assay and Drug Development Technologies, 7(1), 22-43.

Ekonomiuk, D., Su, X. -., Ozawa, K., Bodenreider, C., Siew, P. L., Otting, G., et al. (2009). Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics. Journal of Medicinal Chemistry, 52(15), 4860-4868.

Ekonomiuk, D., Su, X. -., Ozawa, K., Bodenreider, C., Lim, S. P., Yin, Z., et al. (2009). Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking. PLoS Neglected Tropical Diseases, 3(1)

Ellmann, S., Sticht, H., Thiel, F., Beckmann, M. W., Strick, R., & Strissel, P. L. (2009). Estrogen and progesterone receptors: From molecular structures to clinical targets. Cellular and Molecular Life Sciences, 66(15), 2405-2426.

Emerson, C. H. (2009). Circulating thyroid stimulating hormones: Why, when, and what to measure. Thyroid, 19(1), 1-4.

Entzeroth, M., Flotow, H., & Condron, P. (2009). Overview of high-throughput screening. Current Protocols in Pharmacology, (SUPPL. 44), 9.4.1-9.4.27.

Ezgimen, M. D., Mueller, N. H., Teramoto, T., & Padmanabhan, R. (2009). Effects of detergents on the west nile virus protease activity. Bioorganic and Medicinal Chemistry, 17(9), 3278-3282.

Fehrenbacher, J. C., LoVerme, J., Clarke, W., Hargreaves, K. M., Piomelli, D., & Taylor, B. K. (2009). Rapid pain modulation with nuclear receptor ligands. Brain Research Reviews, 60(1), 114-124.

Fenton, R. A. (2009). Essential role of vasopressin-regulated urea transport processes in the mammalian kidney. Pflugers Archiv European Journal of Physiology, 458(1), 169-177.

Fisher, N., Warman, A. J., Ward, S. A., & Biagini, G. A. (2009). Chapter 17 type II NADH: Quinone oxidoreductases of plasmodium falciparum and mycobacterium tuberculosis. kinetic and high-throughput assays

Fix-Stenzel, S. R., Hayes, M. E., Zhang, X., Wallace, G. A., Grongsaard, P., Schaffter, L. M., et al. (2009). A stereoselective and scalable synthesis of a conformationally constrained S1P1 agonist. Tetrahedron Letters, 50(28), 4081-4083.

Foley, T. L., & Burkart, M. D. (2009). A homogeneous resonance energy transfer assay for phosphopantetheinyl transferase. Analytical Biochemistry, 394(1), 39-47.

Foss Jr., F. W., Mathews, T. P., Kharel, Y., Kennedy, P. C., Snyder, A. H., Davis, M. D., et al. (2009). Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugs. Bioorganic and Medicinal Chemistry, 17(16), 6123-6136.

Fowler, R. A., Adhikari, N. K. J., Scales, D. C., Lee, W. L., & Rubenfeld, G. D. (2009). Update in critical care 2008. American Journal of Respiratory and Critical Care Medicine, 179(9), 743-758.

Fox, E. M., Andrade, J., & Shupnik, M. A. (2009). Novel actions of estrogen to promote proliferation: Integration of cytoplasmic and nuclear pathways. Steroids, 74(7), 622-627.

Franchi, L., Eigenbrod, T., Muñoz-Planillo, R., & Nuñez, G. (2009). The inflammasome: A caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nature Immunology, 10(3), 241-247.

Franchi, L., Warner, N., Viani, K., & Nuñez, G. (2009). Function of nod-like receptors in microbial recognition and host defense. Immunological Reviews, 227(1), 106-128.

Fraser, I. D. C., & Germain, R. N. (2009). Navigating the network: Signaling cross-talk in hematopoietic cells. Nature Immunology, 10(4), 327-331.

Gao, J., Sidhu, S. S., & Wells, J. A. (2009). Two-state selection of conformation-specific antibodies. Proceedings of the National Academy of Sciences of the United States of America, 106(9), 3071-3076.

Gasparri, F. (2009). An overview of cell phenotypes in HCS: Limitations and advantages. Expert Opinion on Drug Discovery, 4(6), 643-657.

Gavrilyuk, J. I., Wuellner, U., Salahuddin, S., Goswami, R. K., Sinha, S. C., & Barbas III, C. F. (2009). An efficient chemical approach to bispecific antibodies and antibodies of high valency. Bioorganic and Medicinal Chemistry Letters, 19(14), 3716-3720.

George, S., Kumbhakar, M., Singh, P. K., Ganguly, R., Nath, S., & Pal, H. (2009). Fluorescence spectroscopic investigation to identify the micelle to gel transition of aqueous triblock copolymer solutions. Journal of Physical Chemistry B, 113(15), 5117-5127.

Gerber, A. N., Masuno, K., & Diamond, M. I. (2009). Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. Proceedings of the National Academy of Sciences of the United States of America, 106(12), 4929-4934.

Gil, C., & Bräse, S. (2009). Solid-phase synthesis of biologically active benzoannelated nitrogen heterocycles: An update. Journal of Combinatorial Chemistry, 11(2), 175-197.

Gilbert, D. F., Wilson, J. C., Nink, V., Lynch, J. W., & Osborne, G. W. (2009). Multiplexed labeling of viable cells for high-throughput analysis of glycine receptor function using flow cytometry. Cytometry Part A, 75(5), 440-449.

Gossens, K., Naus, S., Corbel, S. Y., Lin, S., Rossi, F. M. V., Kast, J., et al. (2009). Thymic progenitor homing and lymphocyte homeostasis are linked via s1p-controlled expression of thymic p-selectin/ccl25. Journal of Experimental Medicine, 206(4), 761-778.

Graf, C., Rovina, P., & Bornancin, F. (2009). A secondary assay for ceramide kinase inhibitors based on cell growth inhibition by short-chain ceramides. Analytical Biochemistry, 384(1), 166-169.

Grigorova, I. L., Schwab, S. R., Phan, T. G., Pham, T. H. M., Okada, T., & Cyster, J. G. (2009). Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells. Nature Immunology, 10(1), 58-65.

Guise, T. A., & Brown, S. A. (2009). Cancer treatment-related bone disease. Critical Reviews in Eukaryotic Gene Expression, 19(1), 47-60.

Habig, M., Blechschmidt, A., Dressler, S., Hess, B., Patel, V., Billich, A., et al. (2009). Efficient elimination of nonstoichiometric enzyme inhibitors from HTS hit lists. Journal of Biomolecular Screening, 14(6), 679-689.

Hakamata, W., Kurihara, M., Okuda, H., Nishio, T., & Oku, T. (2009). Design and screening strategies for α-glucosidase inhibitors based on enzymological information. Current Topics in Medicinal Chemistry, 9(1), 3-12.

Hammer, M. M., Kotecha, N., Irish, J. M., Nolan, G. P., & Krutzik, P. O. (2009). WebFlow: A software package for high-throughput analysis of flow cytometry data. Assay and Drug Development Technologies, 7(1), 44-55.

Hammond, R., Mauk, R., Ninaci, D., Nelson, D., & Gibbs, R. B. (2009). Chronic treatment with estrogen receptor agonists restores acquisition of a spatial learning task in young ovariectomized rats. Hormones and Behavior, 56(3), 309-314.

Han, G., Ma, H., Chintala, R., Fulton, D. J. R., Barman, S. A., & White, R. E. (2009). Essential role of the 90-kilodalton heat shock protein in mediating nongenomic estrogen signaling in coronary artery smooth muscle. Journal of Pharmacology and Experimental Therapeutics, 329(3), 850-855.

Hansch, C., & Verma, R. P. (2009). A QSAR study for the cytotoxic activities of taxoids against macrophage (MΦ)-like cells. European Journal of Medicinal Chemistry, 44(1), 274-279.

Hara, T., Hirasawa, A., Sun, Q., Sadakane, K., Itsubo, C., Iga, T., et al. (2009). Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn-Schmiedeberg’s Archives of Pharmacology, 380(3), 247-255.

Harland, L., & Gaulton, A. (2009). Drug target central. Expert Opinion on Drug Discovery, 4(8), 857-872.

Hartung, H. -. (2009). New oral therapies may offer improved treatment options for patients with multiple sclerosis. Current Opinion in Neurology, 22(SUPPL. 1), S10-S14.

Hatae, J., Takami, N., Lin, H., Honda, A., & Inoue, R. (2009). 17β-estradiol-induced enhancement of estrogen receptor biosynthesis via MAPK pathway in mouse skeletal muscle myoblasts. Journal of Physiological Sciences, 59(3), 181-190.

Haynes, M. K., Strouse, J. J., Waller, A., Leitao, A., Curpan, R. F., Bologa, C., et al. (2009). Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt® high-throughput flow cytometry system. Journal of Biomolecular Screening, 14(6), 596-609.

He, M. -., Liu, L., Ge, W., Shaw, P. -., Jiang, R., Wu, L. -., et al. (2009). Antiangiogenic activity of tripterygium wilfordii and its terpenoids. Journal of Ethnopharmacology, 121(1), 61-68.

Hegedus, C., Szakács, G., Homolya, L., Orbán, T. I., Telbisz, Á, Jani, M., et al. (2009). Ins and outs of the ABCG2 multidrug transporter: An update on in vitro functional assays. Advanced Drug Delivery Reviews, 61(1), 47-56.

Herbst, K. J., Allen, M. D., & Zhang, J. (2009). The cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by renilla luciferase. PLoS ONE, 4(5)

Herroeder, S., Reichardt, P., Sassmann, A., Zimmermann, B., Jaeneke, D., Hoeckner, J., et al. (2009). Guanine nucleotide-binding proteins of the G12 family shape immune functions by controlling CD4+ T cell adhesiveness and motility. Immunity, 30(5), 708-720.

Himanen, J. P., Goldgur, Y., Miao, H., Myshkin, E., Guo, H., Buck, M., et al. (2009). Ligand recognition by A-class eph receptors: Crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. EMBO Reports, 10(7), 722-728.

Hiss, D. C., & Gabriels, G. A. (2009). Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. part I: Targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins. Expert Opinion on Drug Discovery, 4(8), 799-821.

Hollins, B., Kuravi, S., Digby, G. J., & Lambert, N. A. (2009). The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers. Cellular Signalling, 21(6), 1015-1021.

Homma, K., Katagiri, K., Nishitoh, H., & Ichijo, H. (2009). Targeting ASK1 in ER stress-related neurodegenerative diseases. Expert Opinion on Therapeutic Targets, 13(6), 653-664.

Huang, X., Cao, J., & Huang, J. (2009). Solid-phase synthesis of benzofused tricycles based on benzimidazole from resin-bound 3-(2-aminophenylamino)-2-seleno-ester. Journal of Combinatorial Chemistry, 11(4), 515-518.

Hutter, M. C. (2009). In silico prediction of drug properties. Current Medicinal Chemistry, 16(2), 189-202.

Ikeda, H., Watanabe, N., Ishii, I., Shimosawa, T., Kume, Y., Tomiya, T., et al. (2009). Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2. Journal of Lipid Research, 50(3), 556-564.

Im, D. -. (2009). New intercellular lipid mediators and their GPCRs: An update. Prostaglandins and Other Lipid Mediators, 89(3-4), 53-56.

Inagi, R. (2009). Endoplasmic reticulum stress in the kidney as a novel mediator of kidney injury. Nephron – Experimental Nephrology, 112(1), e1-e9.

Isensee, J., Meoli, L., Zazzu, V., Nabzdyk, C., Witt, H., Soewarto, D., et al. (2009). Expression pattern of G protein-coupled receptor 30 in LacZ reporter mice. Endocrinology, 150(4), 1722-1723.

Janzen, W. P., & Popa-Burke, I. G. (2009). Review: Advances in improving the quality and flexibility of compound management. Journal of Biomolecular Screening, 14(5), 444-451.

Johnson, R. L., Huang, R., Jadhav, A., Southall, N., Wichterman, J., MacArthur, R., et al. (2009). A quantitative high-throughput screen for modulators of IL-6 signaling: A model for interrogating biological networks using chemical libraries. Molecular BioSystems, 5(9), 1039-1050.

Johnston, R. J., Poholek, A. C., DiToro, D., Yusuf, I., Eto, D., Barnett, B., et al. (2009). Bcl6 and blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science, 325(5943), 1006-1010.

Jonker, N., Kretschmer, A., Kool, J., Fernandez, A., Kloos, D., Krabbe, J. G., et al. (2009). Online magnetic bead dynamic protein-affinity selection coupled to LC-MS for the screening of pharmacologically active compounds. Analytical Chemistry, 81(11), 4263-4270.

Jordan, A. M., & Roughley, S. D. (2009). Drug discovery chemistry: A primer for the non-specialist. Drug Discovery Today, 14(15-16), 731-744.

Judson, R., Richard, A., Dix, D. J., Houck, K., Martin, M., Kavlock, R., et al. (2009). The toxicity data landscape for environmental chemicals. Environmental Health Perspectives, 117(5), 685-695.

Kainkaryam, R. M., & Woolf, P. J. (2009). Pooling in high-throughput drug screening. Current Opinion in Drug Discovery and Development, 12(3), 339-350.

Kalén, M., Wallgard, E., Asker, N., Nasevicius, A., Athley, E., Billgren, E., et al. (2009). Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets. Chemistry and Biology, 16(4), 432-441.

Kamada, K., Arita, N., Tsubaki, T., Takubo, N., Fujino, T., Soga, Y., et al. (2009). Expression of sphingosine kinase 2 in synovial fibroblasts of rheumatoid arthritis contributing to apoptosis by a sphingosine analogue, FTY720. Pathology International, 59(6), 382-389.

Karliner, J. S. (2009). Sphingosine kinase and sphingosine 1-phosphate in cardioprotection. Journal of Cardiovascular Pharmacology, 53(3), 189-197.

Keiser, J., Chollet, J., Xiao, S. -., Mei, J. -., Jiao, P. -., Utzinger, J., et al. (2009). Mefloquine – an aminoalcohol with promising antischistosomal properties in mice. PLoS Neglected Tropical Diseases, 3(1)

Kelly, M. J., & Rønnekleiv, O. K. (2009). Control of CNS neuronal excitability by estrogens via membrane-initiated signaling. Molecular and Cellular Endocrinology, 308(1-2), 17-25.

Keserü, G. M., & Makara, G. M. (2009). The influence of lead discovery strategies on the properties of drug candidates. Nature Reviews Drug Discovery, 8(3), 203-212.

Kim, H., Yoon, S. C., Lee, T. Y., & Jeong, D. (2009). Discriminative cytotoxicity assessment based on various cellular damages. Toxicology Letters, 184(1), 13-17.

Kim, M. H., Kim, M. O., Kim, Y. H., Kim, J. S., & Han, H. J. (2009). Linoleic acid induces mouse embryonic stem cell proliferation via ca 2+/PKC, PI3K/Akt, and MAPKs. Cellular Physiology and Biochemistry, 23(1-3), 53-64.

Kinnings, S. L., Liu, N., Buchmeier, N., Tonge, P. J., Xie, L., & Bourne, P. E. (2009). Drug discovery using chemical systems biology: Repositioning the safe medicine comtan to treat multi-drug and extensively drug resistant tuberculosis. PLoS Computational Biology, 5(7)

Kirchmair, J., Distinto, S., Markt, P., Schuster, D., Spitzer, G. M., Liedl, K. R., et al. (2009). How to optimize shape-based virtual screening: Choosing the right query and including chemical information. Journal of Chemical Information and Modeling, 49(3), 678-692.

Kitambi, S. S., McCulloch, K. J., Peterson, R. T., & Malicki, J. J. (2009). Small molecule screen for compounds that affect vascular development in the zebrafish retina. Mechanisms of Development, 126(5-6), 464-477.

Kitamura, N., Araya, R., Kudoh, M., Kishida, H., Kimura, T., Murayama, M., et al. (2009). Beneficial effects of estrogen in a mouse model of cerebrovascular insufficiency. PLoS ONE, 4(4)

Klabunde, T., Giegerich, C., & Evers, A. (2009). Sequence-derived three-dimensional pharmacophore models for G-protein-coupled receptors and their application in virtual screening. Journal of Medicinal Chemistry, 52(9), 2923-2932.

Kleman-Leyer, K. M., Klink, T. A., Kopp, A. L., Westermeyer, T. A., Koeff, M. D., Larson, B. R., et al. (2009). Characterization and optimization of a red-shifted fluorescence polarization ADP detection assay. Assay and Drug Development Technologies, 7(1), 56-67.

Klinge, C. M. (2009). Estrogen regulation of microRNA expression. Current Genomics, 10(3), 169-183.

Koizumi, K., Shimabara, K., Takemoto, A., Yamazaki, S., Yamauchi, N., Fujii, H., et al. (2009). Palladium-catalyzed heteroarylamination of ethyl 2-chloro-1-azaazulene-3-carboxylate and annulation of heteroarylamino-1-azaazulenes. Heterocycles, 79(C), 319-324.

Kolb, S., Mondésert, O., Goddard, M. -., Jullien, D., Villoutreix, B. O., Ducommun, B., et al. (2009). Development of novel thiazolopyrimidines as CDC25B phosphatase inhibitors. ChemMedChem, 4(4), 633-648.

Köppen, H. (2009). Virtual screening – what does it give us? Current Opinion in Drug Discovery and Development, 12(3), 397-407.

Kozarich, J. W. (2009). The biochemistry of disease: Desperately seeking syzygy

Kralj, D., Friedrich, M., Grošelj, U., Kiraly-Potpara, S., Meden, A., Wagger, J., et al. (2009). A synthesis of 1-substituted 5-[2-(acylamino)ethyl]-1H-pyrazole-4-carboxamides. Tetrahedron, 65(34), 7151-7162.

Krasowski, M. D., Siam, M. G., Iyer, M., & Ekins, S. (2009). Molecular similarity methods for predicting cross-reactivity with therapeutic drug monitoring immunoassays. Therapeutic Drug Monitoring, 31(3), 337-344.

Krewski, D., Andersen, M. E., Mantus, E., & Zeise, L. (2009). Reply to invited commentaries on toxicity testing in the 21st century: Implications for human health risk assessment. Risk Analysis, 29(4), 492-497.

Krewski, D., Andersen, M. E., Mantus, E., & Zeise, L. (2009). Toxicity testing in the 21st century: Implications for human health risk assessment: Perspective. Risk Analysis, 29(4), 474-479.

Kumar, A., & Saba, J. D. (2009). Lyase to live by: Sphingosine phosphate lyase as a therapeutic target. Expert Opinion on Therapeutic Targets, 13(8), 1013-1025.

Lamkanfi, M., & Dixit, V. M. (2009). Inflammasomes: Guardians of cytosolic sanctity. Immunological Reviews, 227(1), 95-105.

LaPensee, E. W., Tuttle, T. R., Fox, S. R., & Ben-Jonathan, N. (2009). Bisphenol A at low nanomolar doses confers chemoresistance in estrogen receptor-α-positive and -negative breast cancer cells. Environmental Health Perspectives, 117(2), 175-180.

Lauer-Fields, J. L., Minond, D., Chase, P. S., Baillargeon, P. E., Saldanha, S. A., Stawikowska, R., et al. (2009). High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate. Bioorganic and Medicinal Chemistry, 17(3), 990-1005.

Lavecchia, A., Di Giovanni, C., & Novellino, E. (2009). CDC25A and B dual-specificity phosphatase inhibitors: Potential agents for cancer therapy. Current Medicinal Chemistry, 16(15), 1831-1849.

Lawrence, H. R., Li, Z., Richard Yip, M. L., Sung, S. -., Lawrence, N. J., McLaughlin, M. L., et al. (2009). Identification of a disruptor of the MDM2-p53 protein-protein interaction facilitated by high-throughput in silico docking. Bioorganic and Medicinal Chemistry Letters, 19(14), 3756-3759.

Lebesgue, D., Reyna-Neyra, A., & Etgen, A. M. (2009). GPR30 differentially regulates short latency responses of luteinising hormone and prolactin secretion to oestradiol. Journal of Neuroendocrinology, 21(9), 743-752.

Lebesgue, D., Chevaleyre, V., Zukin, R. S., & Etgen, A. M. (2009). Estradiol rescues neurons from global ischemia-induced cell death: Multiple cellular pathways of neuroprotection. Steroids, 74(7), 555-561.

Lee, H. -., Smith, M. D., Smith, B. J., Grussendorf, J., Xu, L., Gillies, R. J., et al. (2009). Anticonvulsant met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. ACS Chemical Biology, 4(8), 659-671.

Lee, J. -., Gordon, S., Estrada, R., Wang, L., Siow, D. L., Wattenberg, B. W., et al. (2009). Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature. American Journal of Physiology – Heart and Circulatory Physiology, 296(1), H33-H42.

Levin, E. R. (2009). G protein-coupled receptor 30: Estrogen receptor or collaborator? Endocrinology, 150(4), 1563-1565.

Li, G., & Abdel-Rahman, A. A. (2009). Estrogen-dependent enhancement of NO production in the nucleus tractus solitarius contributes to ethanol-induced hypotension in conscious female rats. Alcoholism: Clinical and Experimental Research, 33(2), 366-374.

Li, J., & Yao, S. Q. (2009). “Singapore green”: A new fluorescent dye for microarray and bioimaging applications. Organic Letters, 11(2), 405-408.

Li, Q., Zhang, S. -., Wang, S. -., & Zhou, M. -. (2009). Efficient synthesis of thalifoline and its analogs. Synthetic Communications, 39(10), 1752-1758.

Li, X. Y., Tan, N. X., Rao, H. B., & Li, Z. R. (2009). Prediction of chemical carcinogenicity by machine learning approaches. SAR and QSAR in Environmental Research, 20(1-2), 27-75.

Li, Y., & Yu, K. -. (2009). Advances in thrombin-protease-activated receptor 1-sphingosine 1-phosphate pathway during sepsis. Chinese Critical Care Medicine, 21(3), 189-191.

Li, Y. -., Cheng, H., Zhu, J. -., Yuan, L., Dai, Y., Cheng, S. -., et al. (2009). Temperature- and pH-sensitive multicolored micellar complexes. Advanced Materials, 21(23), 2402-2406.

Liang, J., Chen, P., & Wu, W. -. (2009). New FRET technique and its application in drug screening. Chinese Pharmaceutical Journal, 44(13), 961-965.

Lieberman, R. L., D’Aquino, J. A., Ringe, D., & Petsko, G. A. (2009). Effects of pH and iminosugar pharmacological chaperones on lysosomal glycosidase structure and stability. Biochemistry, 48(22), 4816-4827.

Lim, M. D., & Craik, C. S. (2009). Using specificity to strategically target proteases. Bioorganic and Medicinal Chemistry, 17(3), 1094-1100.

Lin, B. C., Suzawa, M., Blind, R. D., Tobias, S. C., Bulun, S. E., Scanlan, T. S., et al. (2009). Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation. Cancer Research, 69(13), 5415-5423.

Lindsey, S. H., Cohen, J. A., Brosnihan, K. B., Gallagher, P. E., & Chappell, M. C. (2009). Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.lewis rats. Endocrinology, 150(8), 3753-3758.

Liu, A. -., & Du, G. -. (2009). Research progress of virtual screening aided drug discovery. Yaoxue Xuebao, 44(6), 566-570.

Liu, G., Burns, S., Huang, G., Boyd, K., Proia, R. L., Flavell, R. A., et al. (2009). The receptor S1P1 overrides regulatory T cell-mediated immune suppression through akt-mTOR. Nature Immunology, 10(7), 769-777.

Liverman, C. S., Brown, J. W., Sandhir, R., McCarson, K. E., & Berman, N. E. J. (2009). Role of the oestrogen receptors GPR30 and ERα in peripheral sensitization: Relevance to trigeminal pain disorders in women. Cephalalgia, 29(7), 729-741.

Lønning, P. E. (2009). Lack of complete cross-resistance between different aromatase inhibitors; a real finding in search for an explanation? European Journal of Cancer, 45(4), 527-535.

Lu, X., Sun, C., Valentine, W. J., Shuyu, E., Liu, J., Tigyi, G., et al. (2009). Chiral vinylphosphonate and phosphonate analogues of the immunosuppressive agent FTY720. Journal of Organic Chemistry, 74(8), 3192-3195.

Lü, Z. -., Zou, H. -., Park, S. J., Park, D., Shi, L., Oh, S. H., et al. (2009). The effects of acrylamide on brain creatine kinase: Inhibition kinetics and computational docking simulation. International Journal of Biological Macromolecules, 44(2), 128-132.

Luksha, L., & Kublickiene, K. (2009). The role of estrogen receptor subtypes for vascular maintenance. Gynecological Endocrinology, 25(2), 82-95.

Luo, T., & Schreiber, S. L. (2009). Gold(I)-catalyzed coupling reactions for the synthesis of diverse small molecules using the build/couple/pair strategy. Journal of the American Chemical Society, 131(15), 5667-5674.

Lyssiotis, C. A., Foreman, R. K., Staerk, J., Garcia, M., Mathur, D., Markoulaki, S., et al. (2009). Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States of America, 106(22), 8912-8917.

MacArthur, R., Leister, W., Veith, H., Shinn, P., Southall, N., Austin, C. P., et al. (2009). Monitoring compound integrity with cytochrome P450 assays and qHTS. Journal of Biomolecular Screening, 14(5), 538-546.

MacHleidt, T., Whitney, P., & Bi, K. (2009). Multiplexing of pathway-specific β-lactamase reporter gene assays by optical coding with qtracker® nanocrystals. Journal of Biomolecular Screening, 14(7), 845-852.

Mackman, N. (2009). The many faces of tissue factor. Journal of Thrombosis and Haemostasis, 7(SUPPL. 1), 136-139.

Mak, X. Y., Laurino, P., & Seeberger, P. H. (2009). Synthesis of pharmaceutical and bio-active compounds in microreactors. Chimica Oggi, 27(2), 15-17.

Malissen, B. (2009). Revisiting the follicular helper T cell paradigm. Nature Immunology, 10(4), 371-372.

Marrone, B. L. (2009). Flow cytometry: A multipurpose technology for a wide spectrum of global biosecurity applications. JALA – Journal of the Association for Laboratory Automation, 14(3), 148-156.

Martinon, F., Mayor, A., & Tschopp, J. (2009). The inflammasomes: Guardians of the body

Maru, B. S., Tobias, J. H., Rivers, C., Caunt, C. J., Norman, M. R., & McArdle, C. A. (2009). Potential use of an estrogen-glucocorticoid receptor chimera as a drug screen for tissue selective estrogenic activity. Bone, 44(1), 102-112.

Masters, S. L., Simon, A., Aksentijevich, I., & Kastner, D. L. (2009). Horror autoinflammaticus: The molecular pathophysiology of autoinflammatory disease

McIntire, C. R., Yeretssian, G., & Saleh, M. (2009). Inflammasomes in infection and inflammation. Apoptosis, 14(4), 522-535.

McManus, D. P., Li, Y., Gray, D. J., & Ross, A. G. (2009). Conquering ‘snail fever’: Schistosomiasis and its control in china. Expert Review of Anti-Infective Therapy, 7(4), 473-485.

Means, C. K., & Brown, J. H. (2009). Sphingosine-1-phosphate receptor signalling in the heart. Cardiovascular Research, 82(2), 193-200.

Melville, J. L., Burke, E. K., & Hirst, J. D. (2009). Machine learning in virtual screening. Combinatorial Chemistry and High Throughput Screening, 12(4), 332-343.

Micevych, P., & Dominguez, R. (2009). Membrane estradiol signaling in the brain. Frontiers in Neuroendocrinology, 30(3), 315-327.

Milligan, G., Stoddart, L. A., & Smith, N. J. (2009). Agonism and allosterism: The pharmacology of the free fatty acid receptors FFA2 and FFA3. British Journal of Pharmacology, 158(1), 146-153.

Min, K. H., Yoo, J., & Park, H. -. (2009). Computer-aided identification of ligands for GPCR anti-obesity targets. Current Topics in Medicinal Chemistry, 9(6), 539-553.

Mittal, R., & Bruchez, M. P. (2009). Calibration of flow cytometry for quantitative quantum dot measurements. Current Protocols in Cytometry, (SUPPL. 49), 6.26.1-6.26.7.

Mobley, D. L., & Dill, K. A. (2009). Binding of small-molecule ligands to proteins: “what you see” is not always “what you get”. Structure, 17(4), 489-498.

Mogensen, T. H. (2009). Pathogen recognition and inflammatory signaling in innate immune defenses. Clinical Microbiology Reviews, 22(2), 240-273.

Monie, T. P., Moncrieffe, M. C., & Gay, N. J. (2009). Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling. Immunological Reviews, 227(1), 161-175.

Montón, H., Nogués, C., Rossinyol, E., Castell, O., & Roldán, M. (2009). QDs versus alexa: Reality of promising tools for immunocytochemistry. Journal of Nanobiotechnology, 7

Moy, T. I., Conery, A. L., Larkins-Ford, J., Wu, G., Mazitschek, R., Casadei, G., et al. (2009). High-throughput screen for novel antimicrobials using a whole animal infection model. ACS Chemical Biology, 4(7), 527-533.

Mullershausen, F., Zecri, F., Cetin, C., Billich, A., Guerini, D., & Seuwen, K. (2009). Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors. Nature Chemical Biology, 5(6), 428-434.

Nakai, R., Salisbury, C. M., Rosen, H., & Cravatt, B. F. (2009). Ranking the selectivity of PubChem screening hits by activity-based protein profiling: MMP13 as a case study. Bioorganic and Medicinal Chemistry, 17(3), 1101-1108.

Nandy, J. P., Prakesch, M., Khadem, S., Reddy, P. T., Sharma, U., & Arya, P. (2009). Advances in solution- and solid-phase synthesis toward the generation of natural product-like libraries. Chemical Reviews, 109(5), 1999-2060.

Nguyen, T. D., Jin, X., Lee, K., Hong, Y. -., Young, H. K., & Jung, J. L. (2009). Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from morus species. Journal of Natural Products, 72(1), 39-43.

Nicolle, E., Boumendjel, A., Macalou, S., Genoux, E., Ahmed-Belkacem, A., Carrupt, P. -., et al. (2009). QSAR analysis and molecular modeling of ABCG2-specific inhibitors. Advanced Drug Delivery Reviews, 61(1), 34-46.

Noel, S. D., Keen, K. L., Baumann, D. I., Filardo, E. J., & Terasawa, E. (2009). Involvement of G protein-coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons. Molecular Endocrinology, 23(3), 349-359.

Noor, F., Niklas, J., Müller-Vieira, U., & Heinzle, E. (2009). An integrated approach to improved toxicity prediction for the safety assessment during preclinical drug development using hep G2 cells. Toxicology and Applied Pharmacology, 237(2), 221-231.

O’Neill, L. A. J., Bryant, C. E., & Doyle, S. L. (2009). Therapeutic targeting of toll-like receptors for infectious and inflammatory diseases and cancer. Pharmacological Reviews, 61(2), 177-197.

Ohlsson, C., & Vandenput, L. (2009). The role of estrogens for male bone health. European Journal of Endocrinology, 160(6), 883-889.

Oprea, T. I., Bologa, C. G., Boyer, S., Curpan, R. F., Glen, R. C., Hopkins, A. L., et al. (2009). A crowdsourcing evaluation of the NIH chemical probes. Nature Chemical Biology, 5(7), 441-447.

Otto, C., Fuchs, I., Kauselmann, G., Kern, H., Zevnik, B., Andreasen, P., et al. (2009). GPR30 does not mediate estrogenic responses in reproductive organs in mice. Biology of Reproduction, 80(1), 34-41.

Pandey, D. P., Lappano, R., Albanito, L., Madeo, A., Maggiolini, M., & Picard, D. (2009). Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF. EMBO Journal, 28(5), 523-532.

Pang, Y., & Thomas, P. (2009). Involvement of estradiol-17β and its membrane receptor, G protein coupled receptor 30 (GPR30) in regulation of oocyte maturation in zebrafish, danio rario. General and Comparative Endocrinology, 161(1), 58-61.

Paola Castaldi, M., Troast, D. M., & Porco Jr., J. A. (2009). Stereoselective synthesis of spirocyclic oxindoles via prins cyclizations. Organic Letters, 11(15), 3362-3365.

Papadatos, G., Cooper, A. W. J., Kadirkamanathan, V., Macdonald, S. J. F., McLay, I. M., Pickett, S. P., et al. (2009). Analysis of neighborhood behavior in lead optimization and array design. Journal of Chemical Information and Modeling, 49(2), 195-208.

Park, H., Li, M., Choi, J., Cho, H., & Ham, S. W. (2009). Structure-based virtual screening approach to identify novel classes of Cdc25B phosphatase inhibitors. Bioorganic and Medicinal Chemistry Letters, 19(15), 4372-4375.

Park, S. -., Kim, K. -., An, B. -., Choi, J. -., Jeung, E. -., Leung, P. C. K., et al. (2009). Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38. Journal of Reproduction and Development, 55(1), 23-29.

Parker, L. P., Taylor, D. D., Kesterson, S., & Gercel-Taylor, C. (2009). Gene expression profiling in response to estradiol and genistein in ovarian cancer cells. Cancer Genomics and Proteomics, 6(3), 189-194.

Patel, A., Murray, J., McElwee-Whitmer, S., Bai, C., Kunapuli, P., & Johnson, E. N. (2009). A combination of ultrahigh throughput PathHunter and cytokine secretion assays to identify glucocorticoid receptor agonists. Analytical Biochemistry, 385(2), 286-292.

Peano, B. J., Crabtree, J. S., Komm, B. S., Winneker, R. C., & Harris, H. A. (2009). Effects of various selective estrogen receptor modulators with or without conjugated estrogens on mouse mammary gland. Endocrinology, 150(4), 1897-1903.

Pedra, J. H., Cassel, S. L., & Sutterwala, F. S. (2009). Sensing pathogens and danger signals by the inflammasome. Current Opinion in Immunology, 21(1), 10-16.

Pelegrin, P., & Surprenant, A. (2009). The P2X7 receptor – pannexin connection to dye uptake and IL-1β release. Purinergic Signalling, 5(2), 129-137.

Peltz, S. W., Welch, E. M., Jacobson, A., Trotta, C. R., Naryshkin, N., Sweeney, H. L., et al. (2009). Nonsense suppression activity of PTC124 (ataluren). Proceedings of the National Academy of Sciences of the United States of America, 106(25)

Peternel, L., Kotnik, M., Preželj, A., & Urleb, U. (2009). Comparison of 3 cytotoxicity screening assays and their application to the selection of novel antibacterial hits. Journal of Biomolecular Screening, 14(2), 142-150.

Poholek, A. C., & Craft, J. (2009). Competing for help: New insights into the function of follicular helper T cells. Immunology and Cell Biology, 87(6), 438-439.

Porotto, M., Orefice, G., Yokoyama, C. C., Mungall, B. A., Realubit, R., Sganga, M. L., et al. (2009). Simulating henipavirus multicycle replication in a screening assay leads to identification of a promising candidate for therapy. Journal of Virology, 83(10), 5148-5155.

Prehn, C., Möller, G., & Adamski, J. (2009). Recent advances in 17beta-hydroxysteroid dehydrogenases. Journal of Steroid Biochemistry and Molecular Biology, 114(1-2), 72-77.

Pyne, S., Lee, S. C., Long, J., & Pyne, N. J. (2009). Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease. Cellular Signalling, 21(1), 14-21.

Quinn, J. A., Graeber, C. T., Frackelton Jr., A. R., Kim, M., Schwarzbauer, J. E., & Filardo, E. J. (2009). Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30. Molecular Endocrinology, 23(7), 1052-1064.

Rai, G., Thomas, C. J., Leister, W., & Maloney, D. J. (2009). Synthesis of oxadiazole-2-oxide analogues as potential antischistosomal agents. Tetrahedron Letters, 50(15), 1710-1713.

Reines, I., Kietzmann, M., Mischke, R., Tschernig, T., Lüth, A., Kleuser, B., et al. (2009). Topical application of sphingosine-1-phosphate and FTY720 attenuate allergic contact dermatitis reaction through inhibition of dendritic cell migration. Journal of Investigative Dermatology, 129(8), 1954-1962.

Restif, O. (2009). Evolutionary epidemiology 20 years on: Challenges and prospects. Infection, Genetics and Evolution, 9(1), 108-123.

Reymond, J. -., Fluxà, V. S., & Maillard, N. (2009). Enzyme assays. Chemical Communications, (1), 34-46.

Rivas, M., Mellström, B., Torres, B., Cali, G., Ferrara, A. M., Terracciano, D., et al. (2009). The DREAM protein is associated with thyroid enlargement and nodular development. Molecular Endocrinology, 23(6), 862-870.

Rix, U., & Superti-Furga, G. (2009). Target profiling of small molecules by chemical proteomics. Nature Chemical Biology, 5(9), 616-624.

Rižner, T. L. (2009). Estrogen metabolism and action in endometriosis. Molecular and Cellular Endocrinology, 307(1-2), 8-18.

Roda, A., Guardigli, M., Michelini, E., & Mirasoli, M. (2009). Bioluminescence in analytical chemistry and in vivo imaging. TrAC – Trends in Analytical Chemistry, 28(3), 307-322.

Rogers, N. H., Witczak, C. A., Hirshman, M. F., Goodyear, L. J., & Greenberg, A. S. (2009). Estradiol stimulates akt, AMP-activated protein kinase (AMPK) and TBC1D1/4, but not glucose uptake in rat soleus. Biochemical and Biophysical Research Communications, 382(4), 646-650.

Rohacova, J., Marín, M. L., Martinez-Romero, A., Diaz, L., O’Connor, J. -., Gomez-Lechon, M. J., et al. (2009). Fluorescent benzofurazan-cholic acid conjugates for in vitro assessment of bile acid uptake and its modulation by drugs. ChemMedChem, 4(3), 466-472.

Rohrer, S. G., & Baumann, K. (2009). Maximum unbiased validation (MUV) data sets for virtual screening based on PubChem bioactivity data. Journal of Chemical Information and Modeling, 49(2), 169-184.

Rojo, F., González-Navarrete, I., Bragado, R., Dalmases, A., Menéndez, S., Cortes-Sempere, M., et al. (2009). Mitogen-activated protein kinase phosphatase-1 in human breast cancer independently predicts prognosis and is repressed by doxorubicin. Clinical Cancer Research, 15(10), 3530-3539.

Romero-Sandoval, E. A., Horvath, R., Landry, R. P., & DeLeo, J. A. (2009). Cannabinoid receptor type 2 activation induces a microglial anti-inflammatory phenotype and reduces migration via MKP induction and ERK dephosphorylation. Molecular Pain, 5

Rosen, H., Gonzalez-Cabrera, P. J., Sanna, M. G., & Brown, S. (2009). Sphingosine 1-phosphate receptor signaling

Rosén, J., Lövgren, A., Kogej, T., Muresan, S., Gottfries, J., & Backlund, A. (2009). ChemGPS-NPWeb: Chemical space navigation online. Journal of Computer-Aided Molecular Design, 23(4), 253-259.

Rossi, K. A., Nayeem, A., Weigelt, C. A., & Krystek Jr., S. R. (2009). Closing the side-chain gap in protein loop modeling. Journal of Computer-Aided Molecular Design, 23(7), 411-418.

Saha, S., Qi, J., Wang, S., Wang, M., Li, X., Kim, Y. -., et al. (2009). PGLYRP-2 and Nod2 are both required for peptidoglycan-induced arthritis and local inflammation. Cell Host and Microbe, 5(2), 137-150.

Sakamoto, S., Kabe, Y., Hatakeyama, M., Yamaguchi, Y., & Handa, H. (2009). Development and application of high-performance affinity beads: Toward chemical biology and drug discovery. Chemical Record, 9(1), 66-85.

Sampath, A., & Padmanabhan, R. (2009). Molecular targets for flavivirus drug discovery. Antiviral Research, 81(1), 6-15.

Sánchez, G., de Oliveira Alvares, L., Oberholzer, M. V., Genro, B., Quillfeldt, J., Costa da Costa, J., et al. (2009). M4 muscarinic receptors are involved in modulation of neurotransmission at synapses of schaffer collaterals on CA1 hippocampal neurons in rats. Journal of Neuroscience Research, 87(3), 691-700.

Sánchez-Ollé, G., Duque, J., Egido-Gabás, M., Casas, J., Lluch, M., Chabás, A., et al. (2009). Promising results of the chaperone effect caused by iminosugars and aminocyclitol derivatives on mutant glucocerebrosidases causing gaucher disease. Blood Cells, Molecules, and Diseases, 42(2), 159-166.

SÁnchez-Pedregal, V. M., & Griesinger, C. (2009). The tubulin binding mode of MT stabilizing and destabilizing agents studied by NMR

Sancho, A. G., Wang, X., Sui, B., & Curran, D. P. (2009). Comparison of the relative reactivities of the triisopropylsilyl group with two fluorous analogs. Advanced Synthesis and Catalysis, 351(7-8), 1035-1040.

Satoh, W., Takahashi, S., Sassa, F., Fukuda, J., & Suzuki, H. (2009). On-chip culturing of hepatocytes and monitoring their ammonia metabolism. Lab on a Chip – Miniaturisation for Chemistry and Biology, 9(1), 35-37.

Sattler, K., & Levkau, B. (2009). Sphingosine-1-phosphate as a mediator of high-density lipoprotein effects in cardiovascular protection. Cardiovascular Research, 82(2), 201-211.

Scheiber, J., Chen, B., Milik, M., Sukuru, S. C. K., Bender, A., Mikhailov, D., et al. (2009). Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis. Journal of Chemical Information and Modeling, 49(2), 308-317.

Schlueter, P. J., & Peterson, R. T. (2009). Systematizing serendipity for cardiovascular drug discovery. Circulation, 120(3), 255-263.

Schmitz, C. H. J., Rowat, A. C., Köster, S., & Weitz, D. A. (2009). Dropspots: A picoliter array in a microfluidic device. Lab on a Chip – Miniaturisation for Chemistry and Biology, 9(1), 44-49.

Schneider, G., Hartenfeller, M., Reutlinger, M., Tanrikulu, Y., Proschak, E., & Schneider, P. (2009). Voyages to the (un)known: Adaptive design of bioactive compounds. Trends in Biotechnology, 27(1), 18-26.

Schulz, C., Von Andrian, U., & Massberg, S. (2009). Trafficking of murine hematopoietic stem and progenitor cells in health and vascular disease. Microcirculation, 16(6), 497-507.

Schwede, T., Sali, A., Honig, B., Levitt, M., Berman, H. M., Jones, D., et al. (2009). Outcome of a workshop on applications of protein models in biomedical research. Structure, 17(2), 151-159.

Schwerte, T. (2009). Cardio-respiratory control during early development in the model animal zebrafish. Acta Histochemica, 111(3), 230-243.

Scott, W. L., Alsina, J., Audu, C. O., Babaev, E., Cook, L., Dage, J. L., et al. (2009). Distributed drug discovery, part 2: Global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D3 catalog construction. Journal of Combinatorial Chemistry, 11(1), 14-33.

Scott, W. L., & O’Donnell, M. J. (2009). Distributed drug discovery, part 1: Linking aeademia and combinatorial chemistry to find drug leads for developing world diseases. Journal of Combinatorial Chemistry, 11(1), 3-13.

Sergienko, E., Su, Y., Chan, X., Brown, B., Hurder, A., Narisawa, S., et al. (2009). Identification and characterization of novel tissue-nonspecific alkaline phosphatase inhibitors with diverse modes of action. Journal of Biomolecular Screening, 14(7), 824-837.

Servent, D., & Fruchart-Gaillard, C. (2009). Muscarinic toxins: Tools for the study of the pharmacological and functional properties of muscarinic receptors. Journal of Neurochemistry, 109(5), 1193-1202.

Severin, A., Joseph, R. E., Boyken, S., Fulton, D. B., & Andreotti, A. H. (2009). Proline isomerization preorganizes the itk SH2 domain for binding to the itk SH3 domain. Journal of Molecular Biology, 387(3), 726-743.

Shaw, A. S., & Filbert, E. L. (2009). Scaffold proteins and immune-cell signalling. Nature Reviews Immunology, 9(1), 47-56.

Shaw, J. T. (2009). Naturally diverse: Highlights in versatile synthetic methods enabling target- and diversity-oriented synthesis. Natural Product Reports, 26(1), 11-26.

Shimizu, T. (2009). Lipid mediators in health and disease: Enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation

Silverman, G. A., Luke, C. J., Bhatia, S. R., Long, O. S., Vetica, A. C., Perlmutter, D. H., et al. (2009). Modeling molecular and cellular aspects of human disease using the nematode caenorhabditis elegans. Pediatric Research, 65(1), 10-18.

Singh, N., Guha, R., Giulianotti, M. A., Pinilla, C., Houghten, R. A., & Medina-Franco, J. L. (2009). Chemoinformatic analysis of combinatorial libraries, drugs, natural products, and molecular libraries small molecule repository. Journal of Chemical Information and Modeling, 49(4), 1010-1024.

Sinha, R. K., Park, C., Hwang, I. -., Davis, M. D., & Kehrl, J. H. (2009). B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis. Immunity, 30(3), 434-446.

Slack, M., Winkler, D., Krämer, J., & Hesterkamp, T. (2009). A multiplexed approach to hit finding. Current Opinion in Drug Discovery and Development, 12(3), 351-357.

Slysz, G. W., Baker, C. A. H., Bozsa, B. M., Dang, A., Percy, A. J., Bennett, M., et al. (2009). Hydra: Software for tailored processing of H/D exchange data from MS or tandem MS analyses. BMC Bioinformatics, 10

Smalter, A., Huan, J., & Lushington, G. (2009). Graph wavelet alignment kernels for drug virtual screening. Journal of Bioinformatics and Computational Biology, 7(3), 473-497.

Smiley, D. A., & Khalil, R. A. (2009). Estrogenic compounds, estrogen receptors and vascular cell signaling in the aging blood vessels. Current Medicinal Chemistry, 16(15), 1863-1887.

Smith, P. J., Khan, I. A., & Errington, R. J. (2009). Cytomics and cellular informatics – coping with asymmetry and heterogeneity in biological systems. Drug Discovery Today, 14(5-6), 271-277.

Smits, H. L. (2009). Prospects for the control of neglected tropical diseases by mass drug administration. Expert Review of Anti-Infective Therapy, 7(1), 37-56.

Sölder, E., Kremser, C., Rohr, I., Hutzler, P., & Debbage, P. (2009). Molecular mapping deep within a living human organ: Analysis of microvessel function on the timescale of seconds and with sub-micrometre spatial resolutio. Histochemistry and Cell Biology, 131(5), 537-551.

Solinas, R., DiCesare, J. C., & Baures, P. W. (2009). Parallel synthesis of a library of symmetrically- and dissymmetrically- disubstituted imidazole-4,5-dicarboxamides bearing amino acid esters. Molecules, 14(1), 352-363.

Soulère, L. (2009). Toward docking-based virtual screening for discovering antitubulin agents by targeting taxane and colchicine binding sites. ChemMedChem, 4(2), 161-163.

Spichty, M., Taly, A., Hagn, F., Kessler, H., Barluenga, S., Winssinger, N., et al. (2009). The HSP90 binding mode of a radicicol-like E-oxime determined by docking, binding free energy estimations, and NMR 15N chemical shifts. Biophysical Chemistry, 143(3), 111-123.

Stocks, M. J., Wilden, G. R. H., Pairaudeau, G., Perry, M. W. D., Steele, J., & Stonehouse, J. P. (2009). A practical method for targeted library design balancing lead-like properties with diversity. ChemMedChem, 4(5), 800-808.

Su, X. -., Ozawa, K., Yagi, H., Lim, S. P., Wen, D., Ekonomiuk, D., et al. (2009). NMR study of complexes between low molecular mass inhibitors and the west nile virus NS2B-NS3 protease. FEBS Journal, 276(15), 4244-4255.

Sukocheva, O., Wadham, C., & Xia, P. (2009). Role of sphingolipids in the cytoplasmic signaling of estrogens. Steroids, 74(7), 562-567.

Sukuru, S. C. K., Jenkins, J. L., Beckwith, R. E. J., Scheiber, J., Bender, A., Mikhailov, D., et al. (2009). Plate-based diversity selection based on empirical HTS data to enhance the number of hits and their chemical diversity. Journal of Biomolecular Screening, 14(6), 690-699.

Sweeney, J., Kouttab, N., & Kurtis, J. (2009). Stored red blood cell supernatant facilitates thrombin generation. Transfusion, 49(8), 1569-1579.

Takken, F. L. W., & Tameling, W. I. L. (2009). To nibble at plant resistance proteins. Science, 324(5928), 744-746.

Tan, H. Y., Ng, T. W., & Liew, O. W. (2009). Filterless fluorometry with enhanced sensitivity. Journal of Fluorescence, 19(2), 375-379.

Tao, R., Hoover, H. E., Zhang, J., Honbo, N., Alano, C. C., & Karliner, J. S. (2009). Cardiomyocyte S1P1 receptor-mediated extracellular signal-related kinase signaling and desensitization. Journal of Cardiovascular Pharmacology, 53(6), 486-494.

Terasawa, E., Noel, S. D., & Keen, K. L. (2009). Rapid action of oestrogen in luteinising hormone-releasing hormone neurones: The role of GPR30. Journal of Neuroendocrinology, 21(4), 316-321.

Thammacharoen, S., Geary, N., Lutz, T. A., Ogawa, S., & Asarian, L. (2009). Divergent effects of estradiol and the estrogen receptor-α agonist PPT on eating and activation of PVN CRH neurons in ovariectomized rats and mice. Brain Research, 1268(C), 88-96.

Thorpe, K. L., Maack, G., Benstead, R., & Tyler, C. R. (2009). Estrogenic wastewater treatment works effluents reduce egg production in fish. Environmental Science and Technology, 43(8), 2976-2982.

Tietze, L. F., & Krewer, B. (2009). Novel analogues of CC-1065 and the duocarmycins for the use in targeted tumour therapies. Anti-Cancer Agents in Medicinal Chemistry, 9(3), 304-325.

Titus, S. A., Beacham, D., Shahane, S. A., Southall, N., Xia, M., Huang, R., et al. (2009). A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel. Analytical Biochemistry, 394(1), 30-38.

Tomašić, T., & Mašič, L. P. (2009). Rhodanine as a privileged scaffold in drug discovery. Current Medicinal Chemistry, 16(13), 1596-1629.

Tomlinson, S. M., Malmstrom, R. D., & Watowich, S. J. (2009). New approaches to structure-based discovery of dengue protease inhibitors. Infectious Disorders – Drug Targets, 9(3), 327-343.

Top, S., Thibaudeau, C., Vessières, A., Brulé, E., Le Bideau, F., Joerger, J. -., et al. (2009). Synthesis and structure activity relationship of organometallic steroidal androgen derivatives. Organometallics, 28(5), 1414-1424.

Tu, G., Hu, D., Yang, G., & Yu, T. (2009). The correlation between GPR30 and clinicopathologic variables in breast carcinomas. Technology in Cancer Research and Treatment, 8(3), 231-234.

Turk, S., Kovač, A., Boniface, A., Bostock, J. M., Chopra, I., Blanot, D., et al. (2009). Discovery of new inhibitors of the bacterial peptidoglycan biosynthesis enzymes MurD and MurF by structure-based virtual screening. Bioorganic and Medicinal Chemistry, 17(5), 1884-1889.

Van Den Enden, E. (2009). Pharmacotherapy of helminth infection. Expert Opinion on Pharmacotherapy, 10(3), 435-451.

Villar, H. O., & Hansen, M. R. (2009). Mining and visualizing the chemical content of large databases. Current Opinion in Drug Discovery and Development, 12(3), 367-375.

Vincent, J. -., Artigas, A., Petersen, L. C., & Meyer, C. (2009). A multicenter, randomized, double-blind, placebo-controlled, dose-escalation trial assessing safety and efficacy of active site inactivated recombinant factor VIIa in subjects with acute lung injury or acute respiratory distress syndrome. Critical Care Medicine, 37(6), 1874-1880.

Vogel, P., Donoviel, M. S., Read, R., Hansen, G. M., Hazlewood, J., Anderson, S. J., et al. (2009). Incomplete inhibition of sphingosine 1-phosphate lyase modulates imune system function yet prevents early lethality and non-lymphoid lesions. PLoS ONE, 4(1)

Vogt, A., Cholewinski, A., Shen, X., Nelson, S. G., Lazo, J. S., Tsang, M., et al. (2009). Automated image-based phenotypic analysis in zebrafish embryos. Developmental Dynamics, 238(3), 656-663.

Wagner, R. N., Proell, M., Kufer, T. A., & Schwarzenbacher, R. (2009). Evaluation of nod-like receptor (NLR) effector domain interactions. PLoS ONE, 4(4)

Wallace, G. A., Gordon, T. D., Hayes, M. E., Konopacki, D. B., Fix-Stenzel, S. R., Zhang, X., et al. (2009). Scalable synthesis and isolation of the four stereoisomers of methyl 1-amino-3-(4-bromophenyl)cyclopentanecarboxylate, useful intermediates for the synthesis of S1P1 receptor agonists. Journal of Organic Chemistry, 74(13), 4886-4889.

Walser, M., Pellaux, R., Meyer, A., Bechtold, M., Vanderschuren, H., Reinhardt, R., et al. (2009). Novel method for high-throughput colony PCR screening in nanoliter-reactors. Nucleic Acids Research, 37(8)

Wang, X. -., Li, Q., Wu, J. -., & Tu, S. -. (2009). Efficient method for the synthesis of pyranoquinoline, thiopyranoquinoline, thienoquinoline, and naphtho[2,7]naphthyridine derivatives catalyzed by iodine. Journal of Combinatorial Chemistry, 11(3), 433-437.

Wang, Y., Xiao, J., Suzek, T. O., Zhang, J., Wang, J., & Bryant, S. H. (2009). PubChem: A public information system for analyzing bioactivities of small molecules. Nucleic Acids Research, 37(SUPPL. 2), W623-W633.

Weigert, A., Weis, N., & Brüne, B. (2009). Regulation of macrophage function by sphingosine-1-phosphate. Immunobiology, 214(9-10), 748-760.

Weiler, H., & Kerschen, E. (2009). Modulation of sepsis outcome with variants of activated protein C. Journal of Thrombosis and Haemostasis, 7(SUPPL. 1), 127-131.

Weill, N., & Rognan, D. (2009). Development and validation of a novel protein-ligand fingerprint to mine chemogenomic space: Application to G protein-coupled receptors and their ligands. Journal of Chemical Information and Modeling, 49(4), 1049-1062.

Wellendorph, P., Johansen, L. D., & Bräuner-Osborne, H. (2009). Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients. Molecular Pharmacology, 76(3), 453-465.

Wetzel, S., Klein, K., Renner, S., Rauh, D., Oprea, T. I., Mutzel, P., et al. (2009). Interactive exploration of chemical space with scaffold hunter. Nature Chemical Biology, 5(8), 581-583.

Wheeler, G. N., & Brändli, A. W. (2009). Simple vertebrate models for chemical genetics and drug discovery screens: Lessons from zebrafish and xenopus. Developmental Dynamics, 238(6), 1287-1308.

Williams, N. K., Bamert, R. S., Patel, O., Wang, C., Walden, P. M., Wilks, A. F., et al. (2009). Dissecting specificity in the janus kinases: The structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains. Journal of Molecular Biology, 387(1), 219-232.

Windahl, S. H., Andersson, N., Chagin, A. S., Mårtensson, U. E. A., Carlsten, H., Olde, B., et al. (2009). The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized mice. American Journal of Physiology – Endocrinology and Metabolism, 296(3), E490-E496.

Wu, Y. J., Chen, D. W., Liu, J. L., Zhang, J. H., Luo, H. S., & Cui, S. (2009). Estradiol promotes pituitary cell proliferation and gonadotroph differentiation at different doses and with different mechanisms in chick embryo. Steroids, 74(4-5), 441-448.

Xu, J., Ji, Y., Zhang, X., Drake, M., & Esmon, C. T. (2009). Endogenous activated protein C signaling is critical to protection of mice from lipopolysaccaride-induced septic shock. Journal of Thrombosis and Haemostasis, 7(5), 851-856.

Xu, Y., Su, Y. -., & Yao, Y. -. (2009). Advances in research on pharmacokinetic models of high-throughput screening for drug discovery. Pharmaceutical Care and Research, 9(3), 218-221.

Xu, Y., & Li, X. -. (2009). Multi-target therapeutics and new drug discovery. Yaoxue Xuebao, 44(3), 226-230.

Yang, L., Ho, N. Y., Alshut, R., Legradi, J., Weiss, C., Reischl, M., et al. (2009). Zebrafish embryos as models for embryotoxic and teratological effects of chemicals. Reproductive Toxicology, 28(2), 245-253.

Yarmush, M. L., & King, K. R. (2009). Living-cell microarrays

Yaziji, V., Coelho, A., Maatougui, A. E., Brea, J., Loza, M. I., Garcia-Mera, X., et al. (2009). Divergent solution-phase synthesis of diarylpyrimidine libraries as selective A3 adenosine receptor antagonists. Journal of Combinatorial Chemistry, 11(4), 519-522.

Yet, L. (2009). Chapter 5.4: Five-membered ring systems: With more than one N atom

Yi, C. H., & Yuan, J. (2009). The jekyll and hyde functions of caspases. Developmental Cell, 16(1), 21-34.

Yonesu, K., Ohnuki, T., Ono, Y., Takatsu, T., & Nara, F. (2009). Ascotricins A and B, novel antagonists of sphingosine-1-phosphate receptor 1 from ascotricha chartarum berk. SANK 14186. Journal of Antibiotics, 62(7), 359-364.

Yonesu, K., Kawase, Y., Inoue, T., Takagi, N., Tsuchida, J., Takuwa, Y., et al. (2009). Involvement of sphingosine-1-phosphate and S1P1 in angiogenesis: Analyses using a new S1P1 antagonist of non-sphingosine-1-phosphate analog. Biochemical Pharmacology, 77(6), 1011-1020.

Yu, L., Mohanram, V., Simonson, O. E., Smith, C. I. E., Spetz, A. -., & Mohamed, A. J. (2009). Proteasome inhibitors block HIV-1 replication by affecting both cellular and viral targets. Biochemical and Biophysical Research Communications, 385(1), 100-105.

Yuan, M. -., Shuai, Q., Wang, L., Li, X. -., & Yu, R. -. (2009). 5-bromo-1-methyl-indolin-2-one. Acta Crystallographica Section E: Structure Reports Online, 65(7)

Zallocchi, M., Meehan, D. T., Delimont, D., Askew, C., Garige, S., Gratton, M. A., et al. (2009). Localization and expression of clarin-1, the Clrn1 gene product, in auditory hair cells and photoreceptors. Hearing Research, 255(1-2), 109-120.

Zambianchi, M., Di Maria, F., Cazzato, A., Gigli, G., Piacenza, M., Della Sala, F., et al. (2009). Microwave-assisted synthesis of thiophene fluorophores, labeling and multilabeling of monoclonal antibodies, and long lasting staining of fixed cells. Journal of the American Chemical Society, 131(31), 10892-10900.

Zaragoza-Sundqvist, M., Eriksson, H., Rohman, M., & Greasley, P. J. (2009). High-quality cost-effective compound management support for HTS. Journal of Biomolecular Screening, 14(5), 509-514.

Zhang, C. -., Xiao, S. -., Utzinger, J., Chollet, J., Keiser, J., & Tanner, M. (2009). Histopathological changes in adult schistosoma japonicum harbored in mice treated with a single dose of mefloquine. Parasitology Research, 104(6), 1407-1416.

Zhang, J., Sattler, M., Tonon, G., Grabher, C., Lababidi, S., Zimmerhackl, A., et al. (2009). Targeting angiogenesis via a c-Myc/hypoxia-inducible factor-1α- dependent pathway in multiple myeloma. Cancer Research, 69(12), 5082-5090.

Zhang, Y., Byun, Y., Ren, Y. R., Liu, J. O., Laterra, J., & Pomper, M. G. (2009). Identification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay. Cancer Research, 69(14), 5867-5875.

Zhang, Z., Zhang, Z. -., Fauser, U., & Schluesener, H. J. (2009). Distribution of Foxp3+ T-regulatory cells in experimental autoimmune neuritis rats. Experimental Neurology, 216(1), 75-82.

Zhao, C. -., Deng, Q. -., Zhang, D. -., Cai, W. -., & Zhang, J. -. (2009). Developmental profile and subcellular localization of the non-genomic membranous estrogen receptor GPR30 in the hippocampus of postnatal female rats. Progress in Biochemistry and Biophysics, 36(1), 103-107.

Zhu, H., Ye, L., Richard, A., Golbraikh, A., Wright, F. A., Rusyn, I., et al. (2009). A novel two-step hierarchical quantitative structure-activity relationship modeling work flow for predicting acute toxicity of chemicals in rodents. Environmental Health Perspectives, 117(8), 1257-1264.